Ischaemia-modified albumin levels in newborn jaundice before and after phototherapy

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dc.contributor.authorErdem, Said Sami
dc.contributor.authorKurban, Sevil
dc.contributor.authorAltunhan, Hüseyin
dc.contributor.authorAnnagür, Ali
dc.contributor.authorÖrs, Rahmi
dc.contributor.authorYerlikaya, Fatma Hümeyra
dc.contributor.authorGökçe, Reşat
dc.date.accessioned2020-03-26T18:15:04Z
dc.date.available2020-03-26T18:15:04Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of our study was to assess the effect of phototherapy (PT) on ischaemia-modified albumin (IMA) and malondialdehyde (MDA) levels in hyperbilirubinemic full-term newborns. The study was performed on 36 full-term infants exposed to PT. The babies were aged 3 to 13 days. IMA and MDA levels of the babies were determined before and after PT, by a colorimetric assay. IMA levels before and after PT were found as 0.424 +/- 0.290 and 0.531 +/- 0.262 absorbance units, respectively. Although IMA levels after PT were slightly higher, the difference was not statistically significant (p > 0.131). MDA levels before and after PT were found as 8.4 +/- 1.8 mu mol/l and 9.4 +/- 1.5 mu mol/l, respectively. Serum MDA concentrations were significantly higher after PT than before PT (p < 0.000). In previous studies, conflicting findings have been reported about the effect of PT on oxidant and antioxidant systems. However, we have found no study investigating IMA levels in hyperbilirubinaemia in newborns before and after PT. Our results shows that PT does not affect IMA levels significantly. IMA increases as a result of oxidative stress. We believe that the lack of significant difference between our IMA levels before and after PT may resulted from hyperbilirubinaemia, which has antioxidant effect. Copyright (C) 2011 John Wiley & Sons, Ltd.en_US
dc.identifier.doi10.1002/cbf.1786en_US
dc.identifier.endpage525en_US
dc.identifier.issn0263-6484en_US
dc.identifier.issn1099-0844en_US
dc.identifier.issue6en_US
dc.identifier.pmid21735457en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage521en_US
dc.identifier.urihttps://dx.doi.org/10.1002/cbf.1786
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26596
dc.identifier.volume29en_US
dc.identifier.wosWOS:000294267100011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofCELL BIOCHEMISTRY AND FUNCTIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectphototherapyen_US
dc.subjecthyperbilirubinaemiaen_US
dc.subjectischaemia-modified albuminen_US
dc.subjectmalondialdehydeen_US
dc.titleIschaemia-modified albumin levels in newborn jaundice before and after phototherapyen_US
dc.typeArticleen_US

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