Quality of life in patients with Behcet's disease: the impact of major depression

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dc.contributor.authorUguz, Faruk
dc.contributor.authorDursun, Recep
dc.contributor.authorKaya, Nazmiye
dc.contributor.authorCilli, Ali Savas
dc.date.accessioned2020-03-26T17:18:00Z
dc.date.available2020-03-26T17:18:00Z
dc.date.issued2007
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: Behcet's disease (BD) is a multisystemic inflammatory disorder associated with high levels of depressive symptoms and lower quality of life (QoL). In this study, we aimed to investigate the impact of major depression (MD) on the QoL of patients with BD. Method: BD outpatients (n = 25) and psychiatric outpatients (n = 25) with only MD among the Axis I psychiatric disorders, and BD outpatients (n = 25) and healthy controls (n = 25) without any Axis I psychiatric disorder were included in the study. The Structured Clinical Interview for DSM-IV (SCID-I) was used to determine Axis I psychiatric disorders. Depression and QoL levels were assessed with the Beck Depression Inventory (BDI) and the World Health Organization QoL Assessment-Brief (WHOQOL-BREF), respectively. Results: There was no significant difference with regard to demographic characteristics between the groups. Psychiatric and BD patients with MD had significantly lower overall WHOQOL-BREF subscale scores than BD patients without MD and healthy controls. No significant difference was found in terms of QoL between the groups of psychiatric and BD patients with MD, nor between the groups of BD patients without MD and healthy controls. Overall, there was a significantly negative correlation between all WHOQOL-BREF subscale and BDI scores in BD patients. Conclusion: The study suggests that concurrent MD has a negative impact on QoL of BD patients and that QoL is negatively correlated with the severity of depressive symptoms. (c) 2007 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.genhosppsych.2006.10.001en_US
dc.identifier.endpage24en_US
dc.identifier.issn0163-8343en_US
dc.identifier.issn1873-7714en_US
dc.identifier.issue1en_US
dc.identifier.pmid17189740en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage21en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.genhosppsych.2006.10.001
dc.identifier.urihttps://hdl.handle.net/20.500.12395/21559
dc.identifier.volume29en_US
dc.identifier.wosWOS:000243444000004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.relation.ispartofGENERAL HOSPITAL PSYCHIATRYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBehcet's diseaseen_US
dc.subjectquality of lifeen_US
dc.subjectdepressionen_US
dc.titleQuality of life in patients with Behcet's disease: the impact of major depressionen_US
dc.typeArticleen_US

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