Very Long-term Outcomes After Endoprosthetic Replacement for Malignant Tumours of Bone

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dc.contributor.authorGrimer, Robert J.
dc.contributor.authorAydın, Bahattin Kerem
dc.contributor.authorWafa, Hazem
dc.contributor.authorCarter, S. R.
dc.contributor.authorJeys, Lee M.
dc.contributor.authorAbudu, A.
dc.contributor.authorParry, Michael
dc.date.accessioned2020-03-26T19:31:50Z
dc.date.available2020-03-26T19:31:50Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri, Ortopedi ve Travmatolojien_US
dc.description.abstractAims The aim of this study was to establish what happens to patients in the long term after endoprosthetic replacement for a primary malignant tumour of bone. Patients and Methods We conducted a retrospective analysis of a prospectively maintained database to identify all patients who had undergone an endoprosthetic replacement more than 25 years ago and who were still alive. Their outcomes were investigated with reference to their complications and need for further surgery. A total of 230 patients were identified. Their mean age at diagnosis was 20.7 years (five to 62). The most common diagnosis was osteosarcoma (132). The most common site was the distal femur (102). Results The mean follow-up was 29.4 years (25 to 43). A total of 610 further operations were undertaken, an average of 2.7 further operations per patient. A total of 42 patients (18%) still had the original prosthesis in place. The risk of amputation was 16% at 30 years (31 patients). Those without infection had a mean of 2.1 further operations (one to nine) while those with infection had a mean of 4.6 further operations (two to 11). The risk of infection persisted throughout the life of the prosthesis with a mean of 1% per year becoming infected. Of the 60 patients who developed an infection, 21 (35%) developed this following the primary procedure at a mean of 50 months, but another 19 developed this within a year of another surgical procedure. The risk of infection after any further surgery was 2.7%. The site with the highest risk of infection was the proximal tibia (43.3%).en_US
dc.identifier.citationGrimer, R. J., Aydın, B. K., Wafa, H., Carter, S. R., Jeys, L. M., Abudu, A., Parry, M. (2016). Very long-term outcomes after endoprosthetic replacement for malignant tumours of bone, The Bone & Joint Journal, 98-B, (6), 857-864.
dc.identifier.doi10.1302/0301-620X.98B6.37417en_US
dc.identifier.endpage864en_US
dc.identifier.issn2049-4394en_US
dc.identifier.issue6en_US
dc.identifier.pmid27235533en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage857en_US
dc.identifier.urihttps://dx.doi.org/10.1302/0301-620X.98B6.37417
dc.identifier.urihttps://hdl.handle.net/20.500.12395/34197
dc.identifier.volume98-Ben_US
dc.identifier.wosWOS:000377227800024en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAydın, Bahattin Kerem
dc.language.isoenen_US
dc.publisherThe British Editorial Society of Bone & Joint Surgeryen_US
dc.relation.ispartofThe Bone & Joint Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleVery Long-term Outcomes After Endoprosthetic Replacement for Malignant Tumours of Boneen_US
dc.typeArticleen_US

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