Assessment of Myometrial Invasion in Endometrial Cancer by Transvaginal Sonography, Doppler Ultrasonography, Magnetic Resonance Imaging and Frozen Section

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dc.contributor.authorOzdemir, Suna
dc.contributor.authorCelik, Cetin
dc.contributor.authorEmlik, Dilek
dc.contributor.authorKiresi, Demet
dc.contributor.authorEsen, Hasan
dc.date.accessioned2020-03-26T17:37:55Z
dc.date.available2020-03-26T17:37:55Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: We aimed to compare the diagnostic performance of transvaginal sonography (TVS), magnetic resonance imaging (MRI). and intraoperative frozen section in the assessment of myometrial invasion and to evaluate intratumoral blood flow in any myometrial invasion with transvaginal Color Doppler Ultrasonography (TV-CDU). Methods: This prospective Study included 64 women consecutively diagnosed with endometrial carcinoma. The Subjects were evaluated by TVS, MRI, and TV-CDU by 2 radiologists with a special training in gynecology. Intraoperatively, a frozen section was obtained and processed for interpretation by a blinded pathologist. Sensitivity, specificity, negative, and positive predictive values were calculated for each imaging modality and frozen section with regard to assessment of myometrial invasion. The intratumoral blood flow was evaluated by TV-CDU. Results: Transvaginal sonography, MRI, and frozen section showed no statistical significant differences in overall diagnostic performance for the preoperative and intraoperative assessment of any myometrial invasion, although frozen section seemed to be slightly superior to the imaging techniques. The positive rate of intratumoral blood flow was higher in deep myometrial invasion, but statistical significance was not obtained. The mean value of resistance index was significantly lower in the cases with deep myometrial invasion. Conclusions: Transvaginal sonography with concomitant TV-UCD is low-cost, easily performed, and repeated technique for particularly deep myometrial invasion. Because of its high costs and time-consuming, MRI may be recommended in the cases with poor quality of TVS. Because depending solely oil imaging methods Could lead to insufficient treatment Schedules, intraoperative frozen section should also be performed for myometrial assessment.en_US
dc.identifier.doi10.1111/IGC.0b013e3181ad3eb6en_US
dc.identifier.endpage1090en_US
dc.identifier.issn1048-891Xen_US
dc.identifier.issn1525-1438en_US
dc.identifier.issue6en_US
dc.identifier.pmid19820373en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1085en_US
dc.identifier.urihttps://dx.doi.org/10.1111/IGC.0b013e3181ad3eb6
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23302
dc.identifier.volume19en_US
dc.identifier.wosWOS:000269035200017en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBMJ PUBLISHING GROUPen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCERen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectTransvaginal sonographyen_US
dc.subjectDoppler ultrasonographyen_US
dc.subjectMagnetic resonance imagingen_US
dc.subjectFrozen sectionen_US
dc.subjectEndometrial canceren_US
dc.titleAssessment of Myometrial Invasion in Endometrial Cancer by Transvaginal Sonography, Doppler Ultrasonography, Magnetic Resonance Imaging and Frozen Sectionen_US
dc.typeArticleen_US

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