P-wave Dispersion for Predicting Paroxysmal Atrial Fibrillation in Acute Ischemic Stroke

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dc.contributor.authorDoğan, Umuttan
dc.contributor.authorDoğan, Ebru Apaydın
dc.contributor.authorTekinalp, Mehmet
dc.contributor.authorTokgöz, Osman Serhat
dc.contributor.authorArıbaş, Alpay
dc.contributor.authorAkıllı, Hakan
dc.contributor.authorÖzdemir, Kurtuluş
dc.date.accessioned2020-03-26T18:31:09Z
dc.date.available2020-03-26T18:31:09Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Detection of paroxysmal atrial fibrillation (PAF) in acute ischemic stroke patients poses diagnostic challenge. The aim of this study was to predict the presence of PAF by means of 12-lead ECG in patients with acute ischemic stroke. Our hypothesis was that P-wave dispersion (P-d) might be a useful marker in predicting PAF in patients with acute ischemic stroke. Methods: 12-lead resting ECGs, 24-hour Holter recordings and echocardiograms of 400 patients were analyzed retrospectively. PAF was detected in 40 patients on 24-hour Holter monitoring. Forty out of 360 age and gender matched patients without PAF were randomly chosen and assigned as the control group. Demographics, P-wave characteristics and echocardiographic findings of the patients with and without PAF were compared. Results: Maximum P-wave duration (p=0.002), P-d (p<0.001) and left atrium diameter (p=0.04) were significantly higher in patients with PAF when compared to patients without PAF. However, in binary logistic regression analysis P-d was the only independent predictor of PAF. The cut-off value of P-d for the detection of PAF was 57.5 milliseconds (msc). Area under the curve was 0.80 (p<0.001). On a single 12-lead ECG, a value higher than 57.5 msc predicted the presence of PAF with a sensitivity of 80% and a specificity of 73%. Conclusion: P-d on a single 12-lead ECG obtained within 24 hours of an acute ischemic stroke might help to predict PAF and reduce the risk of recurrent strokes.en_US
dc.identifier.doi10.7150/ijms.9.108en_US
dc.identifier.endpage114en_US
dc.identifier.issn1449-1907en_US
dc.identifier.issue1en_US
dc.identifier.pmid22211098en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage108en_US
dc.identifier.urihttps://dx.doi.org/10.7150/ijms.9.108
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28345
dc.identifier.volume9en_US
dc.identifier.wosWOS:000301065000003en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIVYSPRING INT PUBLen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF MEDICAL SCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectP-wave dispersionen_US
dc.subjectacute ischemic strokeen_US
dc.subject12-lead ECGen_US
dc.subjectparoxysmal atrial fibrillationen_US
dc.subject24-hour Holter monitoringen_US
dc.titleP-wave Dispersion for Predicting Paroxysmal Atrial Fibrillation in Acute Ischemic Strokeen_US
dc.typeArticleen_US

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