Antioxidative effects of cysteamine, hyaluronan and fetuin on post-thaw semen quality, DNA integrity and oxidative stress parameters in the Brown Swiss bull
dc.contributor.author | Sariozkan, S. | |
dc.contributor.author | Tuncer, P. B. | |
dc.contributor.author | Buyukleblebici, S. | |
dc.contributor.author | Bucak, M. N. | |
dc.contributor.author | Canturk, F. | |
dc.contributor.author | Eken, A. | |
dc.date.accessioned | 2020-03-26T19:00:52Z | |
dc.date.available | 2020-03-26T19:00:52Z | |
dc.date.issued | 2015 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | The aim of this study was to compare the effectiveness of antioxidants including cysteamine (2.5, 7.5mm), hyaluronan (0.25, 1mgml(-1)) and fetuin (5, 10mgml(-1)) in the freezing of Brown Swiss bull semen. The best percentages of CASA motilities were achieved with 10mgml(-1) of fetuin and 2.5mm of cysteamine. For sperm morphology, 10mgml(-1) of fetuin and 2.5mm of cysteamine had better protective effects (P<0.001). The results of hypo-osmotic swelling test showed that the percentage values of membrane integrity in all the groups, excluding that supplemented with 5mgml(-1) of fetuin, were higher than those of the control group (P<0.001). Results obtained for the DNA damage of sperm cells demonstrated that 0.25mgml(-1) of hyaluronan, and 2.5 and 7.5mm of cysteamine led to lower rates of spermatozoa with damaged DNA, compared with the control group (P<0.001). The maintenance of superoxide dismutase and glutathione peroxidase antioxidant activities following freeze-thawing with 2.5 and 7.5mm of cysteamine and 10mgml(-1) of fetuin was demonstrated to be at a higher level in comparison with the control group (P<0.001). Malondialdehyde formation was found to be lower in the groups supplemented with 0.25mgml(-1) of hyaluronan and 7.5mm of cysteamine after the freeze-thawing process (P<0.001). | en_US |
dc.identifier.doi | 10.1111/and.12236 | en_US |
dc.identifier.endpage | 147 | en_US |
dc.identifier.issn | 0303-4569 | en_US |
dc.identifier.issn | 1439-0272 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.pmid | 24499020 | en_US |
dc.identifier.scopusquality | Q2 | en_US |
dc.identifier.startpage | 138 | en_US |
dc.identifier.uri | https://dx.doi.org/10.1111/and.12236 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/31848 | |
dc.identifier.volume | 47 | en_US |
dc.identifier.wos | WOS:000348501000002 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | WILEY | en_US |
dc.relation.ispartof | ANDROLOGIA | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.subject | Antioxidant activities | en_US |
dc.subject | cryopreservation | en_US |
dc.subject | DNA damage | en_US |
dc.subject | lipid peroxidation | en_US |
dc.subject | sperm parameters | en_US |
dc.title | Antioxidative effects of cysteamine, hyaluronan and fetuin on post-thaw semen quality, DNA integrity and oxidative stress parameters in the Brown Swiss bull | en_US |
dc.type | Article | en_US |