Is diastolic dysfunction associated with atrial electrocardiographic parameters in Behcet's disease?

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dc.contributor.authorKoc, Fatih
dc.contributor.authorKoc, Sema
dc.contributor.authorYuksek, Jale
dc.contributor.authorVatankulu, Mehmet Akif
dc.contributor.authorOzbek, Kerem
dc.contributor.authorGul, Enes Elvin
dc.contributor.authorCelik, Atac
dc.date.accessioned2020-03-26T18:15:03Z
dc.date.available2020-03-26T18:15:03Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground The impact of Behcet's disease (BD) on the vascular bed is highly important, as this condition may lead to heart failure from asymptomatic systolic and diastolic dysfunction. Our aim was to evaluate diastolic functions using new echocardiographic parameters and the correlation of these parameters with atrial electrocardiographic (ECG) indices in patients with BD. Methods 31 patients with BD and 31 healthy control subjects were enrolled to this study. Left ventricular (LV) diastolic functions were examined with conventional and tissue Doppler echocardiography. P-wave dispersion (PD) was calculated by measuring minimum and maximum P-wave duration values on the 12-lead surface ECG, The relationship between PD and echocardiographic parameters of diastolic dysfunction were investigated. Results The mitral inflow E/A ratio and diastolic myocardial velocity ratio (Em/Am) were lower in the BD group (P < 0.001 and P < 0.001, respectively). The E/Em ratio and left atrial volume index (LAVi) were higher in the BD group (P < 0.001 and P = 0.014, respectively) compared to healthy control subjects. P max and PD were significantly higher in the BD group (P < 0.001 and P < 0.001). PD correlated positively with the duration of BD. Also, PD correlated positively with LAVi and E/Em ratio, but negatively with E/A and Em/Am ratios. Conclusion In this study, we demonstrated that LV diastolic functions are impaired in BD patients. Furthermore, P-wave abnormalities were demonstrated in BD patients and there was a significant correlation between PD and diastolic dysfunction.en_US
dc.identifier.doi10.1080/AC.66.5.2131086en_US
dc.identifier.endpage612en_US
dc.identifier.issn0001-5385en_US
dc.identifier.issn1784-973Xen_US
dc.identifier.issue5en_US
dc.identifier.pmid22032055en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage607en_US
dc.identifier.urihttps://dx.doi.org/10.1080/AC.66.5.2131086
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26593
dc.identifier.volume66en_US
dc.identifier.wosWOS:000295810100007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofACTA CARDIOLOGICAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBehcet's diseaseen_US
dc.subjectdiastolic dysfunctionen_US
dc.subjectleft atrial volume indexen_US
dc.subjectP-wave dispersionen_US
dc.titleIs diastolic dysfunction associated with atrial electrocardiographic parameters in Behcet's disease?en_US
dc.typeArticleen_US

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