Increased bone resorption in the proximal femur in patients with hemiplegia.

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dc.contributor.authorLevendoğlu, Funda
dc.contributor.authorUğurlu, Hatice
dc.contributor.authorGürbilek, Mehmet
dc.contributor.authorAkkurt, Ekrem
dc.contributor.authorKaragözoğlu, Emrah
dc.date.accessioned2020-03-26T16:55:19Z
dc.date.available2020-03-26T16:55:19Z
dc.date.issued2004
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: To investigate the relationship between the proximal femoral bone mineral density and bone resorption markers, determinants of calcium metabolism and vitamin D levels in elderly stroke patients. Design: A total of 80 patients and 20 controls were enrolled in the study. Bone mineral density measurements were obtained at the proximal femur. In all subjects, 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, intact parathyroid hormone, osteocalcin, deoxypyridinoline, and ionized calcium concentrations were measured. Barthel Index and Motricity Index Leg Score were recorded all patients. Results: The serum concentrations of deoxypyridinoline, intact parathyroid hormone, and the mean serum ionized calcium levels were significantly higher in patients with stroke than that of the control subjects. The mean serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentrations in patients were significantly lower than those of the control group (P < 0.05). The bone mineral density of proximal femurs of paretic limbs was decreased significantly compared with those of the control group (P < 0.05). There were significant correlations between the Z score of the hemiplegic side and the patients' Barthel Index, Motricity Index Leg Score, 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, calcium, and deoxypyridinoline. Conclusions: This study provides clear evidence that decreased mobility, vitamin D status, and bone turnover variables in patients after stroke are important factors in the greater bone loss in the paretic leg.en_US
dc.identifier.doi10.1097/01.PHM.0000140802.91648.57en_US
dc.identifier.endpage841en_US
dc.identifier.issn0894-9115en_US
dc.identifier.issue11en_US
dc.identifier.pmid15502736en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage835en_US
dc.identifier.urihttps://dx.doi.org/10.1097/01.PHM.0000140802.91648.57
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19094
dc.identifier.volume83en_US
dc.identifier.wosWOS:000224687300004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofAMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectosteoporosisen_US
dc.subjecthemiplegiaen_US
dc.subjectvitamin Den_US
dc.subjectbone densityen_US
dc.titleIncreased bone resorption in the proximal femur in patients with hemiplegia.en_US
dc.typeArticleen_US

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