Pelvic radiotherapy does not deteriorate the quality of life of women with gynecologic cancers in long-term follow-up: A 2 years prospective single-center study

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dc.contributor.authorYavas, Guler
dc.contributor.authorYavas, Cagdas
dc.contributor.authorDogan, Nasuh Utku
dc.contributor.authorIlhan, Tolgay Tuyan
dc.contributor.authorDogan, Selen
dc.contributor.authorKarabagli, Pinar
dc.contributor.authorAta, Ozlem
dc.date.accessioned2020-03-26T19:42:17Z
dc.date.available2020-03-26T19:42:17Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: To evaluate the emotional, sexual and health-related quality of life (HRQoL) concerns of the women with gynecologic malignancy treated with curative radiotherapy (RT). Patients and Methods: A 100 women with diagnosis of gynecologic malignancy were prospectively enrolled. HRQoL at baseline, at the end of RT and during follow-up was assessed using European Organization for Research and Treatment of Cancer QoL Questionnaire-C30 (EORTC QLQ-C30), EORTC QLQ-cervical cancer module 24, and Hospital Anxiety and Depression Scale. Results: The appetite loss, diarrhea, fatigue, dyspnea, insomnia, nausea and vomiting, pain scores, and sexual activity and sexual enjoyment scores were deteriorated after RT (P = 0.02 for pain scores and P < 0.001 for all other). Body image scores were higher in patients with endometrial cancer (P < 0.01). The emotional function, nausea and vomiting, body image and symptom experience scores were higher in patients who underwent chemotherapy (P = 0.04 and P = 0.01). All the complaints of patients improved during follow-up period. The global health status scores and the level of depression deteriorated in patients with locoregional recurrent disease and distant metastasis. The anxiety (P = 0.001) and depression (P = 0.007) levels were higher in basal and after-RT visits but then decreased through the subsequent follow-up visits. Conclusion: Although pelvic RT deteriorated HRQoL in patients with gynecologic malignancy, HRQoL improved during the follow-up period. The progressive disease had a negative impact on HRQoL.en_US
dc.identifier.doi10.4103/0973-1482.187243en_US
dc.identifier.endpage532en_US
dc.identifier.issn0973-1482en_US
dc.identifier.issn1998-4138en_US
dc.identifier.issue3en_US
dc.identifier.pmid28862221en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage524en_US
dc.identifier.urihttps://dx.doi.org/10.4103/0973-1482.187243
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35369
dc.identifier.volume13en_US
dc.identifier.wosWOS:000409118200025en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMEDKNOW PUBLICATIONS & MEDIA PVT LTDen_US
dc.relation.ispartofJOURNAL OF CANCER RESEARCH AND THERAPEUTICSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectGynecological malignancyen_US
dc.subjectpsychological distressen_US
dc.subjectquality of lifeen_US
dc.subjectradiotherapyen_US
dc.subjectside effectsen_US
dc.titlePelvic radiotherapy does not deteriorate the quality of life of women with gynecologic cancers in long-term follow-up: A 2 years prospective single-center studyen_US
dc.typeArticleen_US

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