Relation of metabolic syndrome with endometrial pathologies in patients with abnormal uterine bleeding

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dc.contributor.authorOzdemir, Suna
dc.contributor.authorBatmaz, Gonca
dc.contributor.authorAtes, Seda
dc.contributor.authorCelik, Cetin
dc.contributor.authorIncesu, Feyzanur
dc.contributor.authorPeru, Celalettin
dc.date.accessioned2020-03-26T19:06:54Z
dc.date.available2020-03-26T19:06:54Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: We aimed to investigate the association of metabolic syndrome and metabolic risk factors with endometrial hyperplasia and carcinoma among women with abnormal uterine bleeding (AUB). Methods: This study included 199 patients who had undergone endometrial curettage due to abnormal uterine bleeding. We divided the patients into two groups according to whether they had an abnormal (n = 53) or normal endometrium (n = 146). Waist circumference, blood pressure, fasting glucose and serum lipid levels were measured and statistically analyzed. The women in each group were matched with regard to mean age, gravidity, parity and menopausal status. Results: We found increased prevalence of metabolic syndrome, diabetes, general and abdominal obesity, hypertension, elevated levels of glucose, total cholesterol and LDL-cholesterol and reduced levels of HDL-cholesterol among women with endometrial carcinoma and hyperplasia. These results were detected particularly in postmenopausal (450 years) women compared to pre-menopausal cases (550 years). All metabolic parameters were similar between hyperplasia and cancer groups. Conclusion: Metabolic syndrome and its components have been shown to have profound impacts on initiation and progession of endometrial pathology, particularly during postmenopausal period.en_US
dc.identifier.doi10.3109/09513590.2015.1058355en_US
dc.identifier.endpage729en_US
dc.identifier.issn0951-3590en_US
dc.identifier.issn1473-0766en_US
dc.identifier.issue9en_US
dc.identifier.pmid26182187en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage725en_US
dc.identifier.urihttps://dx.doi.org/10.3109/09513590.2015.1058355
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32501
dc.identifier.volume31en_US
dc.identifier.wosWOS:000369949900011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofGYNECOLOGICAL ENDOCRINOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectEndometriumen_US
dc.subjectmetabolic syndromeen_US
dc.subjectpathologyen_US
dc.subjectuterine bleedingen_US
dc.titleRelation of metabolic syndrome with endometrial pathologies in patients with abnormal uterine bleedingen_US
dc.typeArticleen_US

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