Digit ratio 2D:4D is a possible indicator for androgenetic alopecia in males

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dc.contributor.authorUnal, Mehmet
dc.date.accessioned2020-03-26T19:53:25Z
dc.date.available2020-03-26T19:53:25Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackgroundAndrogenetic alopecia (AGA) is the most common hair loss. The 2D:4D digit ratio refers to the ratio of the length of the second finger to that of the fourth finger and is thought as a marker of prenatal androgen exposure. ObjectivesThere are many studies which have examined the relationship between 2D:4D ratio and some other diseases. In this study, we evaluated the relationship between digit ratio 2D:4D and AGA. MethodsThe study group was composed of a male with AGA and healthy controls. The lengths of patients' second and fourth fingers were measured using a digital caliper with a resolution of 0.01 mm. Finger length was measured on the palmar side of the hand from the basal metacarpophalangeal crease. The 2D:4D ratio was obtained by dividing the length of the second finger by the length of the fourth finger. ResultsA total of 99 males who have androgenetic alopecia with a score of grade III or more and 90 controls were included. The mean age of AGA group was 29.72 5.53, and the mean age of control group was 19.63 +/- 5.05. The left-hand 2D:4D ratios of AGA group (0.893 +/- 0.267) were significantly lower than healthy controls (0.971 +/- 0.028). No significant relationships were found between AGA severity, age of onset,and digit ratios. ConclusionsThe left-hand digit ratio 2D:4D is lower in AGA patients, and therefore, left-hand digit ratio 2D:4D can be used as an estimation tool for AGA development in future. There is not any correlation between digit ratio and age of onset. Also, there is no correlation between digit ratio 2D:4D and AGA severity.en_US
dc.identifier.doi10.1111/jocd.12403en_US
dc.identifier.endpage548en_US
dc.identifier.issn1473-2130en_US
dc.identifier.issn1473-2165en_US
dc.identifier.issue3en_US
dc.identifier.pmid28856798en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage545en_US
dc.identifier.urihttps://dx.doi.org/10.1111/jocd.12403
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36497
dc.identifier.volume17en_US
dc.identifier.wosWOS:000434129900044en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofJOURNAL OF COSMETIC DERMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectalopeciaen_US
dc.subjectandrogensen_US
dc.subjectdigit ratioen_US
dc.titleDigit ratio 2D:4D is a possible indicator for androgenetic alopecia in malesen_US
dc.typeArticleen_US

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