The role of dental pulp cells in resorption of deciduous teeth
dc.contributor.author | Yildirim, S. | |
dc.contributor.author | Yapar, M. | |
dc.contributor.author | Sermet, U. | |
dc.contributor.author | Sener, K. | |
dc.contributor.author | Kubar, A. | |
dc.date.accessioned | 2020-03-26T17:28:15Z | |
dc.date.available | 2020-03-26T17:28:15Z | |
dc.date.issued | 2008 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | Objective. To address the question whether dental pulp cells of exfoliating human deciduous teeth have some roles for controlling or regulating the root resorption via secreting key molecules (OPG, RANKL, CSF-1, TGF beta, MCP-1 and Cbfa-1) in osteoclastogenesis, we used a sensitive reverse transcriptase polymerase chain reaction (RT-PCR) method for detection of mRNA expressions for the cytokines listed. Study design. The dental pulps were retrieved from incisor and molar teeth in the late stage of shedding (n = 30) and from sound premolar teeth extracted for orthodontic reasons (control group; n = 30). The RT-PCR assays were used to identify targeted gene expression. Results. Of the cytokines examined, RANKL and CSF-1 expressions showed significantly higher occurrence in deciduous dental pulps than in permanent teeth pulpal tissues (P < .040). Conclusions. The findings may suggest an interactive role for pulp tissue cells in the physiologic root resorption process. The cells of dental pulp may have some cytokine-producing cells which mediate monocyte-macrophage lineage to form osteo/odontoclasts, and the RANKL/RANK system might be involved in human deciduous teeth resorption. | en_US |
dc.identifier.doi | 10.1016/j.tripleo.2007.06.026 | en_US |
dc.identifier.endpage | 120 | en_US |
dc.identifier.issn | 1079-2104 | en_US |
dc.identifier.issn | 1528-395X | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.pmid | 17942342 | en_US |
dc.identifier.scopusquality | N/A | en_US |
dc.identifier.startpage | 113 | en_US |
dc.identifier.uri | https://dx.doi.org/10.1016/j.tripleo.2007.06.026 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/22743 | |
dc.identifier.volume | 105 | en_US |
dc.identifier.wos | WOS:000252197200020 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | MOSBY-ELSEVIER | en_US |
dc.relation.ispartof | ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.title | The role of dental pulp cells in resorption of deciduous teeth | en_US |
dc.type | Article | en_US |