The role of dental pulp cells in resorption of deciduous teeth

Basit Öğe Kaydı
dc.contributor.authorYildirim, S.
dc.contributor.authorYapar, M.
dc.contributor.authorSermet, U.
dc.contributor.authorSener, K.
dc.contributor.authorKubar, A.
dc.date.accessioned2020-03-26T17:28:15Z
dc.date.available2020-03-26T17:28:15Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective. To address the question whether dental pulp cells of exfoliating human deciduous teeth have some roles for controlling or regulating the root resorption via secreting key molecules (OPG, RANKL, CSF-1, TGF beta, MCP-1 and Cbfa-1) in osteoclastogenesis, we used a sensitive reverse transcriptase polymerase chain reaction (RT-PCR) method for detection of mRNA expressions for the cytokines listed. Study design. The dental pulps were retrieved from incisor and molar teeth in the late stage of shedding (n = 30) and from sound premolar teeth extracted for orthodontic reasons (control group; n = 30). The RT-PCR assays were used to identify targeted gene expression. Results. Of the cytokines examined, RANKL and CSF-1 expressions showed significantly higher occurrence in deciduous dental pulps than in permanent teeth pulpal tissues (P < .040). Conclusions. The findings may suggest an interactive role for pulp tissue cells in the physiologic root resorption process. The cells of dental pulp may have some cytokine-producing cells which mediate monocyte-macrophage lineage to form osteo/odontoclasts, and the RANKL/RANK system might be involved in human deciduous teeth resorption.en_US
dc.identifier.doi10.1016/j.tripleo.2007.06.026en_US
dc.identifier.endpage120en_US
dc.identifier.issn1079-2104en_US
dc.identifier.issn1528-395Xen_US
dc.identifier.issue1en_US
dc.identifier.pmid17942342en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage113en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.tripleo.2007.06.026
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22743
dc.identifier.volume105en_US
dc.identifier.wosWOS:000252197200020en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMOSBY-ELSEVIERen_US
dc.relation.ispartofORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleThe role of dental pulp cells in resorption of deciduous teethen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu