Immobilization of albumin on aminosilane modified superparamagnetic magnetite nanoparticles and its characterization
Küçük Resim Yok
Tarih
2009
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ELSEVIER SCIENCE BV
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Magnetite nanoparticles (NPs) were synthesized by co-precipitating Fe2+ and Fe3+ in an ammonia solution. Magnetite NPs coated with 3-aminopropyltriethoxysilane (APTES) were prepared by silanization reaction. After activated with glutaraldehyde (CA), human serum albumin was covalently immobilized on these magnetic NPs. The influence of three different buffer solutions on covalent immobilization was studied. phosphate buffer saline solution (PBS) was shown the highest binding ability for immobilization process compared to other buffer solutions. The morphology and properties of these magnetic NPs were examined by transmission electron eicroscopy (TEM), Fourier transform infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA) and magnetization measurement. (C) 2009 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Magnetic nanoparticles, APTES, Silanization, Immobilization, Albumin
Kaynak
COLLOIDS AND SURFACES B-BIOINTERFACES
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
71
Sayı
1