Lack of association between leptin levels and leptin gene polymorphism in obese women

Basit Öğe Kaydı
dc.contributor.authorOkudan, Nilsel
dc.contributor.authorGokbel, Hakki
dc.contributor.authorAcar, Hasan
dc.contributor.authorUzunoglu, Selim
dc.contributor.authorBelviranli, Muaz
dc.date.accessioned2020-03-26T18:51:20Z
dc.date.available2020-03-26T18:51:20Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of the present study was to evaluate the relationship between oligopolymorphism in the 25th codon of leptin gene and obesity. Eighty-seven obese women and 75 healthy women were constituted obese and control groups. Body fat percent, fat mass and lean body mass were determined by bioimpedance meter and leptin levels were determined. The presence of 25th codon oligopolymorphism in the leptin gene was done by PCR-RFLP technique. Mean leptin levels were 38.5 +/- 22.0 ng/ml, and 147.9 +/- 44.8 ng/ml in the control and obese groups, respectively. The correlations of serum leptin level to body fat percentage and fat mass in the control group were significant. The correlations in the obese group were not significant. This data implies that the difference of leptin levels between control and obese groups are more likely to be associated with alterations in the leptin gene other than 25th codon or alterations in the leptin receptor gene.en_US
dc.identifier.doi10.3109/13813455.2014.946933en_US
dc.identifier.endpage139en_US
dc.identifier.issn1381-3455en_US
dc.identifier.issn1744-4160en_US
dc.identifier.issue4en_US
dc.identifier.pmid25117807en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage136en_US
dc.identifier.urihttps://dx.doi.org/10.3109/13813455.2014.946933
dc.identifier.urihttps://hdl.handle.net/20.500.12395/30961
dc.identifier.volume120en_US
dc.identifier.wosWOS:000342767000003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherINFORMA HEALTHCAREen_US
dc.relation.ispartofARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectLeptin geneen_US
dc.subjectobesityen_US
dc.subjectpolymorphismen_US
dc.titleLack of association between leptin levels and leptin gene polymorphism in obese womenen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu