The effect of bispectral index monitoring on cognitive performance following sedation for outpatient colonoscopy: a randomized controlled trial

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dc.contributor.authorSargın, Mehmet
dc.contributor.authorUluer, Mehmet Selçuk
dc.contributor.authorŞimşek, Barış
dc.date.accessioned2020-03-26T20:19:23Z
dc.date.available2020-03-26T20:19:23Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBACKGROUND: Bispectral index (BIS) monitoring can positively affect cognitive performance through decreasing the use of sedative agents. We aimed to evaluate the effect of BIS monitoring on early cognitive performance among patients undergoing sedation for colonoscopy. DESIGN AND SETTING: Randomized, controlled trial in a university hospital. METHODS: 100 patients were randomized into two groups. In the monitored group (n = 50), the depth of anesthesia was monitored using the BIS, and BIS scores were maintained between 60 and 80. In the usual care group (n = 50), BIS monitoring was not performed. To determine the patients' baseline cognitive performance levels, the mini-mental state examination (MMSE), Trieger dot test (TDT) and clock drawing test (CDT) were used. The patients' post-procedure cognitive performance levels were determined when they were classified as ready for discharge. RESULTS: The total volume (mg) of propofol used [median (range) IQR] in the sedation procedure was lower in the monitored group [100 (50-200) 100-140] than in the usual care group [150 (75-200) 100-200] (P < 0.001). The discharge scores [mean (SD)] using MMSE and CDT were higher in the monitored group [26 (3) and 3 (1), respectively] than in the usual care group [23 (3) and 2 (1), respectively] (P = 0.002 and P = 0.002, respectively). The discharge scores using TDT [mean (SD)] were lower in the monitored group [11 (7)] than in the usual care group [15 (11)] (P = 0.033). CONCLUSION: BIS monitoring among sedated patients was associated with lower propofol use and smaller decline in cognitive performance.en_US
dc.identifier.citationSargın, M., Uluer, M. S., Şimşek, B. (2019). The Effect Of Bispectral İndex Monitoring On Cognitive Performance Following Sedation For Outpatient Colonoscopy: A Randomized Controlled Trial. Sao Paulo Medıcal Journal, 137,(4), 305-311.
dc.identifier.doi10.1590/1516-3180.2018.0383210519en_US
dc.identifier.endpage311en_US
dc.identifier.issn1516-3180en_US
dc.identifier.issue4en_US
dc.identifier.pmid31508796en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage305en_US
dc.identifier.urihttps://dx.doi.org/10.1590/1516-3180.2018.0383210519
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38248
dc.identifier.volume137en_US
dc.identifier.wosWOS:000493904600002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSargın, Mehmet
dc.institutionauthorUluer, Mehmet Selçuk
dc.language.isoenen_US
dc.publisherASSOCIACAO PAULISTA MEDICINAen_US
dc.relation.ispartofSAO PAULO MEDICAL JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectConsciousness monitorsen_US
dc.subjectCognitionen_US
dc.subjectConscious sedationen_US
dc.subjectColonoscopyen_US
dc.titleThe effect of bispectral index monitoring on cognitive performance following sedation for outpatient colonoscopy: a randomized controlled trialen_US
dc.typeArticleen_US

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