Effect of Religious Fasting on Tear Osmolarity and Ocular Surface

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dc.contributor.authorKoktekir, Bengu Ekinci
dc.contributor.authorBozkurt, Banu
dc.contributor.authorGonul, Saban
dc.contributor.authorGedik, Sansal
dc.contributor.authorOkudan, Suleyman
dc.date.accessioned2020-03-26T18:50:16Z
dc.date.available2020-03-26T18:50:16Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To evaluate the effects of religious fasting on tear secretion, tear osmolarity, corneal topography, and ocular aberrations. Methods: This prospective controlled study comprised 29 eyes of 29 healthy men. Before ophthalmologic examination, all subjects underwent corneal topography by a placido disc corneal topography and aberrometry device (OPD Scan II). Tear osmolarity was measured using OcuSense TearLab osmometer. Ocular surface disease index (OSDI) scores, tear break-up time (BUT), Schirmer I test, and lissamine green staining were evaluated. The measurements taken before and during Ramadan at the same hours between 4.00 and 5.00 PM were compared using paired sample t test, and a P value less than 0.05 was accepted as statistically significant. Results: The mean age of the study group was 27.8 +/- 5.9 years (range, 20-47 years). The mean tear osmolarity values were measured as 285.6 +/- 8.2 mOsm/L and 293.3 +/- 16.0 mOsm/L, whereas the mean Schirmer I values were 14.8 +/- 6.0 mm and 10.6 +/- 5.3 mm in nonfasting and fasting periods, respectively. Tear osmolarity, OSDI, and Oxford grading scores significantly increased (P=0.02, P=0.002, P=0.003, respectively), whereas Schirmer I values and intraocular pressure decreased (both, P<0.001) during the fasting period compared with the nonfasting period. There were no significant differences in tear BUT, keratometry values, and corneal aberration measurements between nonfasting and fasting periods (P>0.05, for all). Conclusion: Fasting significantly decreases tear production and increases tear osmolarity; however, it does not deteriorate corneal topographic parameters and ocular aberrations in healthy subjects.en_US
dc.identifier.doi10.1097/ICL.0000000000000044en_US
dc.identifier.endpage242en_US
dc.identifier.issn1542-2321en_US
dc.identifier.issn1542-233Xen_US
dc.identifier.issue4en_US
dc.identifier.pmid24874298en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage239en_US
dc.identifier.urihttps://dx.doi.org/10.1097/ICL.0000000000000044
dc.identifier.urihttps://hdl.handle.net/20.500.12395/30780
dc.identifier.volume40en_US
dc.identifier.wosWOS:000338777200009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofEYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectRamadan monthen_US
dc.subjectFastingen_US
dc.subjectTear osmolarityen_US
dc.subjectOcular aberrationsen_US
dc.subjectDry eyeen_US
dc.titleEffect of Religious Fasting on Tear Osmolarity and Ocular Surfaceen_US
dc.typeArticleen_US

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