Central hemodynamics, vascular stiffness, and nocturia in patients with type 2 diabetes

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dc.contributor.authorAfşar, Barış
dc.contributor.authorElsürer, Rengin
dc.date.accessioned2020-03-26T19:01:13Z
dc.date.available2020-03-26T19:01:13Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractRecently, studies have shown that the presence of nocturia may not be a benign condition and related with systemic illness and mortality. Elevated blood pressure (BP) was another factor related with nocturia. Type 2 diabetes mellitus (T2DM) is also associated with nocturia. It is now clear that, apart from peripheral BP, central hemodynamic parameters are important for cardiovascular prognosis. However, no previous study in the literature examined the relationship between nocturia and central hemodynamic parameters in patients with T2DM. The current study was designed to examine these relationships. Nocturia was defined as two or more voids per night. Central hemodynamic parameters were assessed from ambulatory BP measurements. In addition to routine biochemistry, 24-h urine collection was performed to measure protein, albumin, and sodium excretion. 158 patients (52.3%) had T2DM and 144 (47.7%) did not have T2DM (control group). The presence of T2DM was independently related with nocturia. Both in whole group and in T2DM patients, most of the hemodynamic parameters are higher in patients with nocturia compared to patients without nocturia. Among patients with T2DM, nocturia was associated with augmentation index and pulse wave velocity. In conclusion, central hemodynamic parameters and markers of vascular stiffness may be related with nocturia in patients with T2DM.en_US
dc.identifier.doi10.3109/0886022X.2015.1088335en_US
dc.identifier.endpage365en_US
dc.identifier.issn0886-022Xen_US
dc.identifier.issn1525-6049en_US
dc.identifier.issue10en_US
dc.identifier.pmid26381594en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage359en_US
dc.identifier.urihttps://dx.doi.org/10.3109/0886022X.2015.1088335
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31910
dc.identifier.volume37en_US
dc.identifier.wosWOS:000369740400009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofRENAL FAILUREen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectArterial stiffnessen_US
dc.subjectaugmentation indexen_US
dc.subjectblood pressureen_US
dc.subjectdiabetesen_US
dc.subjectnocturiaen_US
dc.subjectpulse wave velocityen_US
dc.titleCentral hemodynamics, vascular stiffness, and nocturia in patients with type 2 diabetesen_US
dc.typeArticleen_US

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