TOTAL OXIDANT STATUS, TOTAL ANTIOXIDANT STATUS, AND PARAOXONASE AND ARYLESTERASE ACTIVITIES DURING LAPAROSCOPIC CHOLECYSTECTOMY

Basit Öğe Kaydı
dc.contributor.authorKoksal, Hande
dc.contributor.authorKurban, Sevil
dc.date.accessioned2020-03-26T18:05:27Z
dc.date.available2020-03-26T18:05:27Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractINTRODUCTION: Laparoscopic cholecystectomy is the gold standard for the treatment of gallstone disease; however, adverse hemodynamic changes induced by increased intraabdominal pressure due to pneumoperitoneum are known to occur. Herein, we investigated the effects of pneumoperitoneum on oxidative stress markers, including paraoxonase, arylesterase, total oxidant status, and total antioxidant status, during laparoscopic cholecystectomy. PATIENTS AND METHODS: Patients that underwent a laparoscopic cholecystectomy were classified as Group I, whereas patients that underwent surgical procedures for an abdominal wall hernia under general anesthesia were classified as Group II. Blood samples were obtained during the preoperative period, the perioperative period, and 24 hours after surgery (postoperative day 1). Leukocyte counts, neutrophil rates, paraoxonase activities, arylesterase activities, and total oxidant and antioxidant status levels were measured. RESULTS: The differences in leukocyte counts and neutrophil rates were not significant between the two groups. In Group I, no significant differences in the total oxidant and antioxidant status levels were identified; however, paraoxonase and arylesterase levels were lower on postoperative day 1. No significant changes were observed in the total oxidant status, total antioxidant status, and paraoxonase or arylesterase activities in Group II. The perioperative total antioxidant status and arylesterase level were higher in Group I in comparison to Group II. CONCLUSION: Paraoxonase and arylesterase levels are useful markers in the evaluation of oxidative stress caused by intraabdominal pressure due to pneumoperitoneum.en_US
dc.identifier.doi10.1590/S1807-59322010000300008en_US
dc.identifier.endpage290en_US
dc.identifier.issn1807-5932en_US
dc.identifier.issn1980-5322en_US
dc.identifier.issue3en_US
dc.identifier.pmid20360919en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage285en_US
dc.identifier.urihttps://dx.doi.org/10.1590/S1807-59322010000300008
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25432
dc.identifier.volume65en_US
dc.identifier.wosWOS:000276689100008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHOSPITAL CLINICAS, UNIV SAO PAULOen_US
dc.relation.ispartofCLINICSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectLaparoscopyen_US
dc.subjectCholecystectomyen_US
dc.subjectParaoxonaseen_US
dc.subjectArylesteraseen_US
dc.subjectOxidative markersen_US
dc.titleTOTAL OXIDANT STATUS, TOTAL ANTIOXIDANT STATUS, AND PARAOXONASE AND ARYLESTERASE ACTIVITIES DURING LAPAROSCOPIC CHOLECYSTECTOMYen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu