Analysis of 87 Patients With Lofgren's Syndrome and the Pattern of Seasonality of Subacute Sarcoidosis

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dc.contributor.authorDemirkök, Sevtap Sipahi
dc.contributor.authorBaşaranoğlu, Metin
dc.contributor.authorDerviş, Emine
dc.contributor.authorBal, Mert
dc.contributor.authorKarayel, Tuncer
dc.date.accessioned2020-03-26T17:03:03Z
dc.date.available2020-03-26T17:03:03Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Sarcoidosis is a multisystem disease of unknown aetiology. The seasonality of sarcoidosis in symptomatic, recently diagnosed patients with Lofgren's syndrome was evaluated to help better understand the possible causative factor(s) in the pathogenesis of sarcoidosis. Methods: Four hundred and ninety-two consecutive patients with sarcoidosis were investigated. The demographic and clinical features, course of the disease, initial diagnostic methods and both the month and age at initial diagnosis for each patient were analysed. Roger's test for cyclic variation was used to determine the significance of any seasonal variation of incidence. Results: Lofgren's syndrome was diagnosed in 87 patients (18%). The diagnosis of sarcoidosis was delayed in 45% of subjects (mean: 11.2 weeks). The distribution of cumulative monthly presentations peaked in May (spring) and was the lowest in January (winter) and November (autumn) (P < 0.001). The seasonal pattern was also influenced by age and gender (P < 0.05). At the onset, arthralgia was present in 46%, cough or dyspnoea in 37%, constitutional symptoms in 32% and skin lesions in 30% of the patients. Conclusions: In this study, there were differences in the amplitude of the seasonal variation by age and by gender. Well-designed prospective studies are required to better understand the importance of the findings we respect to the pathogenesis of the disease.en_US
dc.identifier.citationKarayel, T., Bal, M., Derviş, E., Başaranoğlu, M., Demirkök, S. S., (2006). Analysis of 87 Patients With Lofgren's Syndrome and the Pattern of Seasonality of Subacute Sarcoidosis. Respirology, (11), 456-461. Doi: 10.1111/j.1400-1843.2006.00874.x
dc.identifier.doi10.1111/j.1400-1843.2006.00874.xen_US
dc.identifier.endpage461en_US
dc.identifier.issn1323-7799en_US
dc.identifier.issn1440-1843en_US
dc.identifier.pmid16771916en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage456en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1400-1843.2006.00874.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20328
dc.identifier.volume11en_US
dc.identifier.wosWOS:000237930400012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBaşaranoğlu, Metin
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofRespirologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectageen_US
dc.subjectgenderen_US
dc.subjectsarcoidosisen_US
dc.subjectseasonal variationen_US
dc.titleAnalysis of 87 Patients With Lofgren's Syndrome and the Pattern of Seasonality of Subacute Sarcoidosisen_US
dc.typeArticleen_US

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