Hlas in Children With Minimal Change Disease and Other Types of Nephrotic Syndrome in the Southern Part of Turkey
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish J Pediatrics
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Karabay-Bayazit A, Noyan A, Bayazit Y, Ozel A,Anarat A. HLAs in children with minimal change disease and other types of nephrotic syndrome in the southern part of Turkey. Turk J Pediau 2001; 43: 24-28. The aim of this study was to investigate the human leukocyte antigen (HLA) profile of children with nephrotic syndrome in the southern part of Turkey. Seventy-eight children:with nephrotic syndrome were studied for the frequency of class I and class II human leukocyte antigens. Forty-seven of them were steroid sensitive nephrotic syndrome (minimal change disease-MCD) and 31 were other types of nephrotic syndrome. The results were compared with 133 healthy subjects for HLA groups. HLA B13, Cw5, Cw7, DR4 DR7, DRw10, Drw15(2) and DQ2 in the MCD group and HLA A31, B8, B13, B17, Cw2, Cw6, Cw7, DRw10 and DRw12 in the non-MCD group were found significantly increased when compared to healthy controls. MCD patients with frequent relapses had higher frequencies of both Cw6 and DR1 (p < 0.005) and MCD patients with infrequent relapses had a higher frequency of Cw7 (p < 0.05). In conclusion, HLA groups may help in the early diagnosis of these variants.
Açıklama
Anahtar Kelimeler
HLA, nephrotic syndrome, Turkish children
Kaynak
Turkish Journal of Pediatrics
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
43
Sayı
1
Künye
Karabay Bayazıt, A., Noyan, A., Bayazıt, Y., Özel, A., Anarat, A., (2001). Hlas in Children With Minimal Change Disease and Other Types of Nephrotic Syndrome in the Southern Part of Turkey. Turkish Journal of Pediatrics, 43(1), 24-28.
