The association between pulmonary arterial hypertension and malnutrition in children with congenital heart diseases with left-to-right shunt: an observational study

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dc.contributor.authorAltın, Hakan
dc.contributor.authorKarataş, Zehra
dc.contributor.authorSap, Fatih
dc.contributor.authorAlp, Hayrullah
dc.contributor.authorBaysal, Tamer
dc.contributor.authorKaraaslan, Sevim
dc.contributor.authorOran, Bülent
dc.date.accessioned2020-03-26T18:31:33Z
dc.date.available2020-03-26T18:31:33Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To evaluate the association between the degree of pulmonary arterial hypertension (PAH) and the level of malnutrition in children with acyanotic congenital heart diseases and left-to-right shunt, and especially to evaluate the development rates of malnutrition in patients with borderline PAH. Methods: The study was performed with data of 327 patients with acyanotic congenital heart diseases and left-to-right shunt and underwent cardiac catheterization between January 2001-February 2011. The design of the study was retrospective and observational. All patients were evaluated with anthropometric measurements, echocardiography and cardiac catheterization. They were classified according to the mean pulmonary artery pressure and level of malnutrition. Chi-square, ANOVA and Kruskal-Wallis tests were used for statistical analysis. Normally and abnormally distributed data were analyzed with Pearson and Spearman correlation tests respectively. Results: Malnutrition was detected in 94.8% of patients with PAH and 17.2% of no PAN patients according to Gomez classification (p<0.001). In addition, malnutrition was detected in 23.5% (16/68) of borderline PAN group. A negative association was detected between mean pulmonary arterial pressure and body weight for age (Gomez) and z scores of weight (p<0.001 for all). Z scores of weight and height were significantly decreased in patients with PAH in contrast to no PAH group (p<0.001, p<0.01 respectively). There was no statistical difference between no PAH and borderline PAH groups according to Gomez classification and relative body weight formula, however z scores of weight in borderline PAN group were decreased compared with no PAH group (p<0.001). Conclusion: A positive association was detected between the degrees of PAH and level of malnutrition in children with a cyanotic congenital heart diseases with left-to-right shunt. Borderline PAH may be a predisposing factor for malnutrition and further studies are needed for this subject. (Anadolu Kardiyol Derg 2012; 12: 150-9)en_US
dc.identifier.doi10.5152/akd.2012.041en_US
dc.identifier.endpage159en_US
dc.identifier.issn2149-2263en_US
dc.identifier.issn2149-2271en_US
dc.identifier.issue2en_US
dc.identifier.pmid22306568en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage150en_US
dc.identifier.urihttps://dx.doi.org/10.5152/akd.2012.041
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28474
dc.identifier.volume12en_US
dc.identifier.wosWOS:000300797800011en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherTURKISH SOC CARDIOLOGYen_US
dc.relation.ispartofANATOLIAN JOURNAL OF CARDIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectChilden_US
dc.subjectmalnutritionen_US
dc.subjectcongenital heart diseaseen_US
dc.subjectpulmonary arterial hypertensionen_US
dc.titleThe association between pulmonary arterial hypertension and malnutrition in children with congenital heart diseases with left-to-right shunt: an observational studyen_US
dc.typeArticleen_US

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