Takayasu arteritis in a 4-year-old girl: case report and brief overview of the pediatric literature
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Dosyalar
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
TURKISH J PEDIATRICS
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Takayasu arteritis (TA) is a large vessel vasculitis that involves the aorta, its major branches and pulmonary arteries. Diagnosis of TA during childhood remains challenging due to the non-specific symptoms. We report a fouryear- old girl presenting with fever, fatigue, weight loss, and elbow pain who was later diagnosed as childhood TA. On admission, she had fever, hypertension, decreased pulses, bruits, hepatosplenomegaly, and increased erythrocyte sedimentation rate and C-reactive protein level. Computed tomography angiography showed luminal narrowing and wall thickening in ascending aorta, brachiocephalic, left common carotid and left vertebral arteries and descending aorta. Oral corticosteroid (prednisone, 2 mg/kg/day) was instituted, later followed by oral methotrexate (12.5 mg/m(2)/week). TA is rare in children; however, childhood TA must be considered in children who present with non-specific systemic symptoms, hypertension and increased acute phase reactants.
Açıklama
Anahtar Kelimeler
Takayasu arteritis, vasculitis, hypertension, children
Kaynak
TURKISH JOURNAL OF PEDIATRICS
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
54
Sayı
5
