Mangafodipir trisodium-enhanced magnetic resonance imaging for evaluation of pancreatic mass and mass-like lesions

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dc.contributor.authorEser, Gul
dc.contributor.authorKarabacakoglu, Aydin
dc.contributor.authorKarakose, Serdar
dc.contributor.authorEser, Cengiz
dc.contributor.authorKayacetin, Ertugrul
dc.date.accessioned2020-03-26T17:03:52Z
dc.date.available2020-03-26T17:03:52Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAIM: To investigate the role of mangafodipir trisodium (MnDPDP) in focal pancreatic masses and mass-like lesions by evaluating contrast uptake features of the lesions and pancreatic parenchyma after contrast medium injection. METHODS: A total of 37 patients with pancreatic mass or mass-like lesions were examined by unenhanced and MnDPDP-enhanced magnetic resonance imaging (MRI). RESULTS: MRI was obtained 20-40 min after infusion of MnDPDP and homogeneous contrast enhancement was observed in normal pancreas parenchyma. In patients with atrophic pancreas there was no enhancement in pancreatic parenchyma on MnDPDP-enhanced MRI. In 37 patients with 41 pancreatic masses and mass-like lesions, contrast enhancement was observed at 5 lesions on MnDPDP enhanced MRI. Three of these 5 lesions were focal pancreatitis and the other 2 were adenocarcinoma. No contrast enhancement was determined in 36 pancreatic masses and mass-like lesions in 32 patients. CONCLUSION: MnDPDP contrast-enhanced MRI, especially in cases with no parenchyma atrophy, can distinguish focal pancreatic lesion margins. Information about the function of pancreatic parenchyma can be obtained out of tumor. MnDPDP facilitates staging of pancreatic tumors by detection of metastatic lesions in the liver. In addition, diminished heteregenous uptake of MnDPDP in patients with pancreatitis may be helpful in differential diagnosis. (C) 2006 The WJG Press. All rights reserved.en_US
dc.identifier.doi10.3748/wjg.v12.i10.1603en_US
dc.identifier.endpage1606en_US
dc.identifier.issn1007-9327en_US
dc.identifier.issue10en_US
dc.identifier.pmid16570354en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1603en_US
dc.identifier.urihttps://dx.doi.org/10.3748/wjg.v12.i10.1603
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20574
dc.identifier.volume12en_US
dc.identifier.wosWOS:000239995600016en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW J G PRESSen_US
dc.relation.ispartofWORLD JOURNAL OF GASTROENTEROLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectMnDPDPen_US
dc.subjectpancreasen_US
dc.subjectMRIen_US
dc.titleMangafodipir trisodium-enhanced magnetic resonance imaging for evaluation of pancreatic mass and mass-like lesionsen_US
dc.typeArticleen_US

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