Circadian Rhythm of Infarct Size and Left Ventricular Function Evaluated with Tissue Doppler Echocardiography in ST Elevation Myocardial Infarction

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dc.contributor.authorArı, Hatem
dc.contributor.authorSönmez, Osman
dc.contributor.authorKoç, Fatih
dc.contributor.authorDemir, Kenan
dc.contributor.authorAlihanoğlu, Yusuf İzzettin
dc.contributor.authorÖzdemir, Kurtuluş
dc.contributor.authorVatankulu, Mehmet Akif
dc.date.accessioned2020-03-26T19:23:19Z
dc.date.available2020-03-26T19:23:19Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground We aimed to investigate the circadian rhythm on left ventricular (LV) function and infarct size, according to the onset of ST elevation myocardial infarction (STEMI), with echocardiography in patients with first STEMI successfully revascularised with primary percutaneous coronary intervention (PCI). Methods We conducted a retrospective analysis of 252 STEMI patients. Patients were divided into the four, six-hour periods of the day. Conventional and tissue Doppler imaging (TDI) echocardiography were performed within 48 hours after onset of chest pain. The average of peak systolic myocardial velocities (Sm) in each of the four myocardial segments and LV ejection fraction (LVEF) were calculated. Results A negative linear correlation was shown between CK-MB levels and Sm (r= -0.209, p = 0.001). There was an oscillation between time of day and average of Sm. The lowest Sm and largest infarct size were in the period of 06: 00-noon compared with period of noon-18: 00 and 18: 00-midnight (p = 0.029 and p = 0.031, respectively). A secondary analysis showed that both LVEF and Sm were lower in the midnight-noon group compared with the noon-midnight group (44.9 +/- 7.3% versus 47.3 +/- 7.9%, p = 0.018, and 7.6 +/- 1.4 cm/s versus 8.2 +/- 1.6 cm/s, p= 0.003, respectively). Conclusions This study has shown that there was a circadian rhythm of infarct size and LV function evaluated by echocardiography according to time of STEMI onset. The largest infarct size and poor LV function occurred in the midnight-noon period, in particular in the 06: 00-noon period.en_US
dc.identifier.doi10.1016/j.hlc.2015.06.833en_US
dc.identifier.endpage256en_US
dc.identifier.issn1443-9506en_US
dc.identifier.issn1444-2892en_US
dc.identifier.issue3en_US
dc.identifier.pmid26475647en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage250en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.hlc.2015.06.833
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33352
dc.identifier.volume25en_US
dc.identifier.wosWOS:000370263500016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.relation.ispartofHEART LUNG AND CIRCULATIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCircadianen_US
dc.subjectMyocardial infarct sizeen_US
dc.subjectMyocardial infarctionen_US
dc.subjectTissue Doppleren_US
dc.subjectLeft ventricular functionen_US
dc.subjectEchocardiographyen_US
dc.titleCircadian Rhythm of Infarct Size and Left Ventricular Function Evaluated with Tissue Doppler Echocardiography in ST Elevation Myocardial Infarctionen_US
dc.typeArticleen_US

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