Effect of Selenium Supplementation on Lipid Peroxidation, Antioxidant Enzymes, and Lactate Levels in Rats Immediately After Acute Swimming Exercise

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dc.contributor.authorAkil, Mustafa
dc.contributor.authorGurbuz, Umit
dc.contributor.authorBicer, Mursel
dc.contributor.authorSivrikaya, Abdullah
dc.contributor.authorMogulkoc, Rasim
dc.contributor.authorBaltaci, Abdulkerim Kasim
dc.date.accessioned2020-03-26T18:14:17Z
dc.date.available2020-03-26T18:14:17Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe present study aims to evaluate the effect of selenium supplementation on lipid peroxidation and lactate levels in rats subjected to acute swimming exercise. Thirty-two adult male rats of Sprague-Dawley type were divided into four groups. Group 1, control; group 2, selenium-supplemented; group 3, swimming control; group 4, selenium-supplemented swimming group. The animals in groups 2 and 4 were supplemented with (i.p.) 6 mg/kg/day sodium selenite for 4 weeks. The blood samples taken from the animals by decapitation method were analyzed in terms of erythrocyte-reduced glutathione (GSH), serum glutathione peroxidase (GPx) and superoxide dismutase (SOD), and plasma malondialdehyde (MDA) and lactate using the colorimetric method, and serum selenium values using an atomic emission device. In the study, the highest MDA and lactate values were found in group 3, while the highest GSH, GPx and SOD values were obtained in group 4 (p < 0,001). Group 2 had the highest and group 3 had the lowest selenium levels (p < 0,001). Results of the study indicate that the increase in free radical production and lactate levels due to acute swimming exercise in rats might be offset by selenium supplementation. Selenium supplementation may be important in that it supports the antioxidant system in physical activity.en_US
dc.identifier.doi10.1007/s12011-010-8785-zen_US
dc.identifier.endpage659en_US
dc.identifier.issn0163-4984en_US
dc.identifier.issue3en_US
dc.identifier.pmid20680512en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage651en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s12011-010-8785-z
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26376
dc.identifier.volume142en_US
dc.identifier.wosWOS:000293706900037en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHUMANA PRESS INCen_US
dc.relation.ispartofBIOLOGICAL TRACE ELEMENT RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectSeleniumen_US
dc.subjectExerciseen_US
dc.subjectFree radicalsen_US
dc.subjectAntioxidant activityen_US
dc.subjectLactateen_US
dc.titleEffect of Selenium Supplementation on Lipid Peroxidation, Antioxidant Enzymes, and Lactate Levels in Rats Immediately After Acute Swimming Exerciseen_US
dc.typeArticleen_US

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