Specific Dermatologic Features of the Polycystic Ovary Syndrome and Its Association with Biochemical Markers of the Metabolic Syndrome and Hyperandrogenism

dc.contributor.authorÖzdemir, Suna
dc.contributor.authorÖzdemir, Mustafa
dc.contributor.authorGörkemli, Hüseyin
dc.contributor.authorKıyıcı, Aysel
dc.contributor.authorBodur, Sait
dc.date.accessioned2020-03-26T18:05:02Z
dc.date.available2020-03-26T18:05:02Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective. To investigate biochemical and metabolic abnormalities in relation with cutaneous features of polycystic ovary syndrome (PCOS). Design. Prospective descriptive analysis. Setting. University-based tertiary care. Sample. One-hundred and fifteen untreated consecutive women diagnosed as having PCOS. Methods. Each woman underwent an evaluation of body habitus, acne, hirsutism, seborrhea, androgenic alopecia and acanthosis nigricans. Associations between cutaneous features and hormonal and metabolic parameters were analyzed by means of multivariate logistic regression models. Main outcome measures. Prevalence of cutaneous features in PCOS and associations among the features and biochemical and metabolic parameters. Results. The prevalence of acne, hirsutism, seborrhea, androgenetic alopecia and acanthosis nigricans was 53%, 73.9%, 34.8%, 34.8% and 5.2%, respectively. Acne was not associated with the hormonal, metabolic and anthropometric variables. Hirsutism had positive associations with total testosterone, fasting glucose and total cholesterol, and a negative association with age. Seborrhea was found to be related with free testosterone, fasting glucose and insulin. A negative association was determined among androgenic alopecia and free testosterone, low-density lipoprotein and insulin. Conclusions. Acne and androgenic alopecia are not good markers for the hyperandrogenism in PCOS. Hirsutism appears to be strongly related with hyperandrogenism and metabolic abnormalities in PCOS women.en_US
dc.identifier.citationÖzdemir, S., Özdemir, M., Görkemli, H., Kıyıcı, A., Bodur, S., (2010). Specific Dermatologic Features of the Polycystic Ovary Syndrome and Its Association with Biochemical Markers of the Metabolic Syndrome and Hyperandrogenism. Acta Obstetricia Et Gynecologica Scandinavica, 89(2), 199-204.
dc.identifier.endpage204en_US
dc.identifier.issn0001-6349en_US
dc.identifier.issn1600-0412en_US
dc.identifier.issue2en_US
dc.identifier.pmid19900078en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage199en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25277
dc.identifier.volume89en_US
dc.identifier.wosWOS:000275251800007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzdemir, Suna
dc.institutionauthorÖzdemir, Mustafa
dc.institutionauthorGörkemli, Hüseyin
dc.institutionauthorKıyıcı, Aysel
dc.institutionauthorBodur, Sait
dc.language.isoenen_US
dc.publisherWILEY-BLACKWELLen_US
dc.relation.ispartofActa Obstetricia Et Gynecologica Scandinavicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPolycystic Ovary Syndromeen_US
dc.subjectCutaneous Featuresen_US
dc.subjectHyperandrogenismen_US
dc.subjectMetabolic Abnormalityen_US
dc.titleSpecific Dermatologic Features of the Polycystic Ovary Syndrome and Its Association with Biochemical Markers of the Metabolic Syndrome and Hyperandrogenismen_US
dc.typeArticleen_US

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