Simultaneous occurrence of chronic myelogenous leukemia and non-Hodgkin lymphoma at diagnosis
Küçük Resim Yok
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ELSEVIER SCIENCE INC
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
We describe a case with the simultaneous occurrence of chronic myelogenous leukemia (CML) and non-Hodgkin lymphoma (NHL). Peripheral blood (PB) and bone marrow (BM) smears showed typical CML features. Lymph node biopsy exhibited a large-cell NHL. The Philadelphia chromosome or ifs molecular counterpart, the BCR-ABL gene fusion, by detecting with dual color-(DC) fluorescence in situ hybridization (FISH) was detected reliably both in metaphase spreads from BM and in interphase nuclei from BM and follow-up PB cells, but was not detected in the lymph node cells. Clinical features and laboratory findings show this case having a coexistence of CML and NHL. (C) Elsevier Science Inc., 1998.
Açıklama
Anahtar Kelimeler
Kaynak
CANCER GENETICS AND CYTOGENETICS
WoS Q Değeri
Q2
Scopus Q Değeri
N/A
Cilt
108
Sayı
2