The role of immunonutrition in gynecologic oncologic surgery

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dc.contributor.authorCelik, J. B.
dc.contributor.authorGezginc, K.
dc.contributor.authorOzcelik, K.
dc.contributor.authorCelik, C.
dc.date.accessioned2020-03-26T17:40:49Z
dc.date.available2020-03-26T17:40:49Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: This study assesses the effect of immunonutrition on biochemical and hematological parameters, incidence of infection, postoperative complications, mortality rate and length of hospital stay. Material and Methods: A total of 50 patients operated on for gynecological malignancies were randomly assigned to two groups, each receiving two days preoperative and seven days postoperative enteral nutrition after intestinal movements started. The patients in group 1 were given 1000 kcal/d immun-enhancing enteral nutrition (IEN). The patients in group 2 received 1000 kcal/d standard enteral nutrition. The nutritional (albumin, prealbumin). immunologic (CRP, white blood cell (WBC) count, lymphocyte population) parameters, length of hospital stay (LOS) and clinical outcomes were examined. Results: The two groups did not differ in terms of demogaphic data, nutritional status, surgical status. mortality rate (p > 0.05). WBC count, lymphocyte population. CRP levels were significantly higher in group 1 compared with group 2 in the postoperative period (p < 0.05). Pulmonary and urinary tract infection rates were similar in both groups (p > 0.05) but Wound infection, and LOS rate were significantly lower in group 1 than group 2 (p < 0.05). Conclusion: Perioperative immunonutrition proved to be safe and useful in increasing the immunologic response. It may decrease postoperative complications and LOS in patients undergoing surgery for gynecological malignancy.en_US
dc.identifier.endpage421en_US
dc.identifier.issn0392-2936en_US
dc.identifier.issue4en_US
dc.identifier.pmid19761135en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage418en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23966
dc.identifier.volume30en_US
dc.identifier.wosWOS:000268089400015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisher7847050 CANADA INCen_US
dc.relation.ispartofEUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectGynecological malignancyen_US
dc.subjectImmunonutritionen_US
dc.subjectComplicationsen_US
dc.titleThe role of immunonutrition in gynecologic oncologic surgeryen_US
dc.typeArticleen_US

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