Topical Anesthetic Abuse Keratopathy: A Commonly Overlooked Health Care Problem

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dc.contributor.authorYagci, Ayse
dc.contributor.authorBozkurt, Banu
dc.contributor.authorEgrilmez, Sait
dc.contributor.authorPalamar, Melis
dc.contributor.authorOzturk, Banu Turgut
dc.contributor.authorPekel, Hamiyet
dc.date.accessioned2020-03-26T18:17:20Z
dc.date.available2020-03-26T18:17:20Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: To evaluate the clinical course, treatment modality, factors affecting the epithelization period, and visual outcome in patients with topical anesthetic abuse keratopathy. Methods: The medical records of 19 patients with a confirmed diagnosis of topical anesthetic abuse keratopathy were retrospectively examined; occupation, initiating event, biomicroscopic findings, treatment modality, epithelization period, and best-corrected visual acuity (BCVA) were noted. The Wilcoxon signed rank test was used to compare BCVA before and after treatment; P values < 0.05 were considered statistically significant. Results: In all, 26 eyes in 19 men aged 21-44 (mean age: 31 +/- 6) years were included. Initiating events included exposure to arc welding flash (8 patients), metallic foreign body injury (8 patients), and chemical injury (3 patients). On admission to hospital, 10 patients (52.6%) reported that they were using topical anesthetics. Upon admission to the hospital, 10 patients (52.6%) self reported that they were using topical anesthetics. The remaining 9 subjects were discovered to be using topical anaesthetic drops during hospitalization. Twelve patients (63.2%) were found to continue using these agents during their hospitalization. Oval corneal epithelial defect, stromal infiltrate, ring-shaped keratitis, and hypopyon were noted in 100%, 46.2%, 57.7%, and 42.3% of the eyes, respectively. Topical antibiotics (fluoroquinolones or combined fortified cephalosporins and aminoglycosides), preservative-free lubricants/autologous serum, and bandage contact lens/eye patches were used for treatment. Mean epithelization period was 19.96 +/- 11.16 days (range: 6-50 days). Mean pretreatment and posttreatment BCVA was 0.12 +/- 0.16 (range: 0.001-0.7) and 0.66 +/- 0.30 (range: 0.0-1.0), respectively (P < 0.001). Conclusions: Ophthalmologists should be suspicious of topical anesthetic abuse keratopathy in young male manual laborers specialized in welding business and foundry work presenting with persistent epithelial defects, ring-shaped keratitis, and accompanying severe ocular pain.en_US
dc.identifier.doi10.1097/ICO.0b013e3182000af9en_US
dc.identifier.endpage575en_US
dc.identifier.issn0277-3740en_US
dc.identifier.issue5en_US
dc.identifier.pmid21598429en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage571en_US
dc.identifier.urihttps://dx.doi.org/10.1097/ICO.0b013e3182000af9
dc.identifier.urihttps://hdl.handle.net/20.500.12395/27015
dc.identifier.volume30en_US
dc.identifier.wosWOS:000289142600015en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofCORNEAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjecttopical anesthetic abuseen_US
dc.subjectoccupationen_US
dc.subjectpersistent epithelial defecten_US
dc.subjectcorneal ulceren_US
dc.subjectring keratitisen_US
dc.titleTopical Anesthetic Abuse Keratopathy: A Commonly Overlooked Health Care Problemen_US
dc.typeArticleen_US

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