Multiorgan Dysfunction Accompanied With Metimazole and Thyroid Storm

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dc.contributor.authorKulaksızoğlu, Mustafa
dc.contributor.authorGönen, Mustafa Sait
dc.contributor.authorKebapçılar, Levent
dc.contributor.authorŞahin, Fatih
dc.contributor.authorAçıkgöz, Burcu
dc.contributor.authorDemir, Tarık
dc.contributor.authorDinçtürk, Ekrem
dc.date.accessioned2020-03-26T18:30:55Z
dc.date.available2020-03-26T18:30:55Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractA 41-year-old man with a history of hyperthyroidism had been treated with methimazole and propranolol for the past 2 months. He developed multiorgan dysfunction with acute liver failure, severe lactic acidosis, disseminated intravascular coagulation, heart failure and acute pulmonary edema with rapid deterioration of renal function. The patient had no history of alcoholism, drug abuse, blood transfusion, or exposure to hepatitis A, B, or C. Extrahepatic obstruction was ruled out with an abdominal ultrasonogram. Serologic studies and immunologic tests were negative. This case illustrates the sudden and abrupt deterioration of multiorgan dysfunction due to antithyroid drug administration and thyroid storm. The thyroid storm score of Burch and Wartofsky was 90/140. The multiorgan dysfunction was reversed by discontinuation of the methimazole and treat with hemodialysis, steroids, cholestyramine, nonselective beta-blocker, fresh frozen plasma infusion and supportive management in the intensive care unit. The patient was discharged from the hospital with normal coagulation parameters, renal and liver function tests. (C) 2012 Elsevier Ltd. All rights reserved.en_US
dc.identifier.citationKulaksızoğlu, M., Gönen, M. S., Kebapçılar, L., Şahin, F., Açıkgöz, B., Demir, T., Dinçtürk, E., (2012). Multiorgan Dysfunction Accompanied With Metimazole and Thyroid Storm. Transfusion and Apheresis Science, 46(2), 149-152. Doi:10.1016/j.transci.2012.01.001
dc.identifier.doi10.1016/j.transci.2012.01.001en_US
dc.identifier.endpage152en_US
dc.identifier.issn1473-0502en_US
dc.identifier.issue2en_US
dc.identifier.pmid22284265en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage149en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.transci.2012.01.001
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28250
dc.identifier.volume46en_US
dc.identifier.wosWOS:000302826800006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKulaksızoğlu, Mustafa
dc.institutionauthorGönen, Mustafa Sait
dc.institutionauthorKebapçılar, Levent
dc.institutionauthorŞahin, Fatih
dc.institutionauthorAçıkgöz, Burcu
dc.institutionauthorDemir, Tarık
dc.institutionauthorDinçtürk, Ekrem
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofTransfusion and Apheresis Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectThyroid stormen_US
dc.subjectAcute liver failureen_US
dc.subjectMetimazoleen_US
dc.subjectMultiorgan dysfunctionen_US
dc.subjectHyperthyroidismen_US
dc.titleMultiorgan Dysfunction Accompanied With Metimazole and Thyroid Stormen_US
dc.typeArticleen_US

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