Does Ventriculoperitoneal Shunting Improve Thyroid Hormone Levels in Hydrocephalic Newborns?

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dc.contributor.authorÜçler, Necati
dc.contributor.authorErol, Fatih Serhat
dc.contributor.authorÖztürk, Sait
dc.contributor.authorAkgün, Bekir
dc.contributor.authorKaplan, Metin
dc.contributor.authorŞen, Yaşar
dc.date.accessioned2020-03-26T19:34:58Z
dc.date.available2020-03-26T19:34:58Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective/Aim: The aim of this report was to investigate the effect of ventriculoperitoneal shunt insertion for the treatment of hydrocephalus on thyroid hormones in the first 3 months of life. Methods: Thyroid-stimulating hormone (TSH), free T3 (fT3), and free T4 (fT4) levels were compared at 7 days (preoperatively) and at 30 and 90 days (postoperatively) after birth between 25 ventriculoperitoneal shunt-inserted hydrocephalic newborns and 20 healthy newborns. Results: The TSH level at 7 days was higher in the hydrocephalic patient group (6.33 mu IU) compared to the control group (3.76 mu IU). This value was significantly decreased at 90 days in the ventriculoperitoneal shunt-inserted newborns (2.35 mu IU) compared to the control group (3.33 mu IU; p < 0.05). There were no significant differences between time points for fT4 and fT3 values in the patient group or for TSH, fT4, and fT3 values in the control group. Conclusion: We propose that a ventriculoperitoneal shunt inserted in the early period of life may have beneficial effects on thyroid hormones. (C) 2016 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000448050en_US
dc.identifier.endpage29en_US
dc.identifier.issn1016-2291en_US
dc.identifier.issn1423-0305en_US
dc.identifier.issue1en_US
dc.identifier.pmid27490332en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage26en_US
dc.identifier.urihttps://dx.doi.org/10.1159/000448050
dc.identifier.urihttps://hdl.handle.net/20.500.12395/34981
dc.identifier.volume52en_US
dc.identifier.wosWOS:000397060900005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKARGERen_US
dc.relation.ispartofPEDIATRIC NEUROSURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHydrocephalusen_US
dc.subjectHypothyroidismen_US
dc.subjectThyroid hormonesen_US
dc.subjectVentriculoperitoneal shunten_US
dc.titleDoes Ventriculoperitoneal Shunting Improve Thyroid Hormone Levels in Hydrocephalic Newborns?en_US
dc.typeArticleen_US

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