Effects of menopause on the myocardial velocities and myocardial performance index

Basit Öğe Kaydı
dc.contributor.authorDuzenli, Mehmet Akif
dc.contributor.authorOzdemir, Kurtulus
dc.contributor.authorSokmen, Abdullah
dc.contributor.authorSoylu, Ahmet
dc.contributor.authorAygul, Nazif
dc.contributor.authorGezginc, Kazim
dc.contributor.authorTokac, Mehmet
dc.date.accessioned2020-03-26T17:17:22Z
dc.date.available2020-03-26T17:17:22Z
dc.date.issued2007
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground Although menopause is known to increase cardiovascular risk and mortality, the effect of menopause on cardiac functions has not been investigated in detail. This study investigates the effect of menopause on cardiac functions by tissue Doppler echocardiography (TDE) and myocardial performance index (MPI). Methods and Results A total of 72 postmenopausal and 71 age-matched premenopausal women were enrolled in the study. After conventional echocardiographic parameters were measured, TDE recordings were obtained at the septal, lateral, anterior and inferior side of the mitral annulus, and tricuspid lateral annulus. Systolic velocity (Sm), early and late diastolic velocities (Em and Am) and time intervals were measured and MPI was calculated. A sequentially symptom-limited exercise stress test was performed. Although left ventricular (LV) ejection fraction and end-diastolic and end-systolic diameter were similar in both groups, LV septum and posterior wall thickness were higher in postmenopausal women. Mitral early inflow velocity and mitral early inflow velocity:mitral late inflow velocity ratio were significantly lower in postmenopausal women compared to premenopausal women. LV Sm, and LV and right ventricular (RV) Em:Am ratios were lower in postmenopausal women. MPI calculated by TDE was significantly increased in postmenopausal women. In addition, exercise duration and metabolic equivalent values were significantly lower in postmenopausal women than in premenopausal women. Conclusions Menopause negatively affects MPI and myocardial velocities, both of which provide more quantitative data about myocardial functions. These findings indicate that the hormonal changes in menopause impair LV systolic and diastolic functions and RV diastolic function.en_US
dc.identifier.doi10.1253/circj.71.1728en_US
dc.identifier.endpage1733en_US
dc.identifier.issn1346-9843en_US
dc.identifier.issue11en_US
dc.identifier.pmid17965492en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1728en_US
dc.identifier.urihttps://dx.doi.org/10.1253/circj.71.1728
dc.identifier.urihttps://hdl.handle.net/20.500.12395/21370
dc.identifier.volume71en_US
dc.identifier.wosWOS:000250657500010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJAPANESE CIRCULATION SOCen_US
dc.relation.ispartofCIRCULATION JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcardiac functionsen_US
dc.subjectmenopauseen_US
dc.subjectmyocardial performance indexen_US
dc.subjecttissue Doppler echocardiographyen_US
dc.titleEffects of menopause on the myocardial velocities and myocardial performance indexen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu