Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species

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dc.contributor.authorAktümsek, Abdurrahman
dc.contributor.authorZengin, Gökhan
dc.contributor.authorGüler, Gökalp Özmen
dc.contributor.authorÇakmak, Yavuz Selim
dc.contributor.authorDuran, Ahmet
dc.date.accessioned2020-03-26T18:41:07Z
dc.date.available2020-03-26T18:41:07Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe methanol and aqueous extracts of three endemic Centaurea species (C. polypodiifolia var. pseudobehen, C pyrrhoblephara and C antalyense) were investigated for their antioxidant and cholinesterase inhibitory activities. The antioxidant activities of these extracts were evaluated by in vitro models including, phosphomolybdenum assay, free radical scavenging assays (DPPH and ABTS), beta-carotene/linoleic acid test system, metal chelating assay, FRAP assay, ferric and cupric reducing power. Cholinesterase inhibitory activities were examined using Ellman's calorimetric method. Total phenol, flavonoid, and saponin contents were also measured. Among the six Centaurea extracts evaluated, the highest antioxidant abilities were obtained from C polypodiifolia var. pseudobehen. Methanolic extracts from C polypodiifolia var. pseudobehen and C antalyense had a noticeable inhibition towards AChE and BChE. These findings suggest that Centaurea species could be an anticholinesterase agent and antioxidant resource in some industries, such as food, pharmacology, and cosmetics. (C) 2013 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipSelcuk University Scientific Research Foundation (BAP)Selcuk University; [11401066]en_US
dc.description.sponsorshipThis study was supported financially as a project (11401066). The authors thank Selcuk University Scientific Research Foundation (BAP) for providing financial support for this study. The authors also want to thank Dr. Harun Simsek for proofreading the present manuscript.en_US
dc.identifier.doi10.1016/j.fct.2013.01.018en_US
dc.identifier.endpage296en_US
dc.identifier.issn0278-6915en_US
dc.identifier.issn1873-6351en_US
dc.identifier.pmid23357566en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage290en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.fct.2013.01.018
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29227
dc.identifier.volume55en_US
dc.identifier.wosWOS:000317536900038en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDen_US
dc.relation.ispartofFOOD AND CHEMICAL TOXICOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCentaureaen_US
dc.subjectAntioxidanten_US
dc.subjectPhenolicsen_US
dc.subjectAnticholinesterase activityen_US
dc.titleAntioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. speciesen_US
dc.typeArticleen_US

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