Prophylactic Efficiency of 3-Weekly Benzathine Penicillin G in Rheumatic Fever
Yükleniyor...
Dosyalar
Tarih
2000
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
The Indian Journal of Pediatrics
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Benzathine penicillin G (BPG) is effective for secondary prophylaxis of rheumatic fever (RF). However, interval between injections a remains a controversial matter. In a study population of 74 patients, following the initial diagnosis of RF, 3-weekly BPG (1.2 million units) regimen was started. During the first three-week period, serum penicillin concentrations were examined on the 7th, 14th and 21st days and throat done for group-A b hemolytic streptococcal (GABHS) infection. Ten patients (13.5%) at 21st day of injection had low serum penicillin concentration after the first BPG. GABHS was isolated in 5 patients during this period. Although two of these 5 patients had symptoms of respiratory tract infection, according to laboratory data, the other three were accepted as carriers. There was no PR among regular (missing no more than one injection a year) group. We concluded that 3-weekly BPG regimen was satisfactory for secondary prophylaxis in RF, even though serum penicillin level was inadequate during the third week in some of the patients.
Açıklama
Anahtar Kelimeler
Benzathine penicillin G., Rheumatic fever, Secondary prophylaxis
Kaynak
Indian Journal of Pediatrics
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
67
Sayı
3
Künye
Oran, B., Taştekin, A., Karaaslan, S., Baş, L., Ayçiçek, A., Çeri, A., Sütçü, A., Erkul, İ., (2000). Prophylactic Efficiency of 3-Weekly
Benzathine Penicillin G in Rheumatic Fever. Indian Journal of Pediatrics, 67(3), 163-167. Doi: 10.1007/BF02723652
