Serum IL-1?, IL-6, IL-10 and TNF-? levels in thyroidectomized rats

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dc.contributor.authorKandir, Sinan
dc.contributor.authorKeskin, Ercan
dc.date.accessioned2020-03-26T19:26:17Z
dc.date.available2020-03-26T19:26:17Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesi, Veteriner Fakültesi, Temel Bilimler Bölümüen_US
dc.description.abstractThis study was conducted to determine the serum levels of interleukin (IL)-1 beta, IL-6, IL-10 and tumor necrosis factor alpha (TNF-alpha) in thyroidectomized rats. Hypothyroidism was performed by surgical thyroidectomy in rats. Four weeks after from surgical procedure, selected cytokines levels were evaluated. Hypothyroidism was confirmed by elevated thyroid stimulating hormone (TSH) and decreased free tri-iodothyronine (fT3) levels (P<0.05) in thyroidectomized group. Serum IL-1 beta, IL-6, IL-10 levels have shown slight increase, whereas only TNF-alpha level (P<0.05) were significant statistically in thyroidectomized rats compared with control group. In conclusion, the obtained data suggest that elevated levels of cytokines could be as a consequence of thyroidectomy operation.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)/ARDEB 1002 Short Term R&D Funding Program [115O130]en_US
dc.description.sponsorshipThis project was partially supported by The Scientific and Technological Research Council of Turkey (TUBITAK)/ARDEB 1002 Short Term R&D Funding Program (Project No: 115O130)en_US
dc.identifier.citationKandır, S., Keskin, E. (2016). Serum IL-1β, IL-6, IL-10 and TNF-α Levels in Thyroidectomized Rats. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 22(2), 297-300.
dc.identifier.doi10.9775/kvfd.2015.14371en_US
dc.identifier.endpage300en_US
dc.identifier.issn1300-6045en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage297en_US
dc.identifier.urihttps://dx.doi.org/10.9775/kvfd.2015.14371
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33982
dc.identifier.volume22en_US
dc.identifier.wosWOS:000374311900021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKandir, Sinan
dc.institutionauthorKeskin, Ercan
dc.language.isoenen_US
dc.publisherKAFKAS UNIV, VETERINER FAKULTESI DERGISIen_US
dc.relation.ispartofKAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISIen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCytokineen_US
dc.subjectImmune functionen_US
dc.subjectRodenten_US
dc.subjectThyroid alterationen_US
dc.subjectTraumaen_US
dc.titleSerum IL-1?, IL-6, IL-10 and TNF-? levels in thyroidectomized ratsen_US
dc.title.alternativeTiroidektomize ratlarda serum IL-1?, IL-6, IL-10 ve TNF-? seviyelerien_US
dc.typeArticleen_US

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