Long-term outcomes of pulmonary vein isolation using second-generation cryoballoon during atrial fibrillation ablation

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dc.contributor.authorCanpolat, Ugur
dc.contributor.authorKocyigit, Duygu
dc.contributor.authorYalcin, Muhammed Ulvi
dc.contributor.authorCoteli, Cem
dc.contributor.authorSener, Yusuf Ziya
dc.contributor.authorOksul, Metin
dc.contributor.authorGurses, Kadri Murat
dc.contributor.authorEvranos, Banu
dc.contributor.authorYorgun, Hikmet
dc.contributor.authorAytemir, Kudret
dc.date.accessioned2020-03-26T20:15:05Z
dc.date.available2020-03-26T20:15:05Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground Currently available second-generation cryoballoon (CB2) is accepted as an effective and safe tool for pulmonary vein isolation (PVI). Although much more data exist about 1-year outcomes of CB2 ablation, data on long-term outcomes are scarce. Objective We aimed to assess the long-term outcomes of PVI using CB2 in a large-scale symptomatic atrial fibrillation (AF) population at our tertiary referral center. Methods In this nonrandomized prospective observational study, a total of 486 patients with paroxysmal (71%) or persistent (29%) AF who underwent index PVI using CB2 at our hospital between January 2013 and June 2017 were enrolled. Atrial tachyarrhythmia (ATa)-free survival was defined as the absence of AF, atrial flutter, or atrial tachycardia recurrence >= 30 s following a 3 months blanking period. Predictors of recurrence were evaluated by univariate and multivariate Cox proportional hazards regression models. Results Acute procedural success rate was 99.8% (1898/1902 PVs). Mean procedural and fluoroscopy time were 64.9 +/- 9.2 and 12.1 +/- 2.6, respectively. At median 39 (interquartile range: 26-56) months follow-up, ATa-free survival was 78.6% after a single procedure (280/345 [81.2%] for paroxysmal AF vs. 102/141 [72.3%] for persistent AF, P = .019) and 84.4% after a mean 1.48 +/- 0.42 ablations. Cox regression analysis showed that left atrium diameter, duration of AF history, and early ATa recurrence were found as the independent predictors of late recurrence. Phrenic nerve palsy was observed in 17 (3.5%) patients. Conclusions CB2-based PVI is effective to maintain sinus rhythm in a significant proportion of paroxysmal and persistent AF patients with an acceptable complication rate at long-term follow-up.en_US
dc.identifier.citationCanpolat, U., Kocyigit, D., Yalcin, M. U., Coteli, C., Sener, Y. Z., Oksul, M., Gurses, K. M., Evranos, B., Yorgun, H., Aytemir, K. (2019). Long‐Term Outcomes Of Pulmonary Vein İsolation Using Second‐Generation Cryoballoon During Atrial Fibrillation Ablation. Pacing And Clinical Electrophysiology, 42,(7), 910-921.
dc.identifier.doi10.1111/pace.13721en_US
dc.identifier.endpage921en_US
dc.identifier.issn0147-8389en_US
dc.identifier.issn1540-8159en_US
dc.identifier.issue7en_US
dc.identifier.pmid31106431en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage910en_US
dc.identifier.urihttps://dx.doi.org/10.1111/pace.13721
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37982
dc.identifier.volume42en_US
dc.identifier.wosWOS:000474649700019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYalcin, Muhammed Ulvi
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofPACE-PACING AND CLINICAL ELECTROPHYSIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectatrial fibrillationen_US
dc.subjectcomplicationen_US
dc.subjectcryoballoonen_US
dc.subjectrecurrenceen_US
dc.titleLong-term outcomes of pulmonary vein isolation using second-generation cryoballoon during atrial fibrillation ablationen_US
dc.typeArticleen_US

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