Effect of Phenobarbital on Antioxidant Enzyme Activities and Blood Gas Parameters in Balb/C Mice
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ECOLE NATIONALE VETERINAIRE TOULOUSE
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, effect of Phenobarbital was investigated on antioxidant enzyme activities and blood gas parameters in Balb/C mice. Forty male Balb/C mice were used. Ten mice were served as a control group, and thirty mice were administered phenobarbital (80 mg/kg body weight, orally, single administration). Blood, brain and liver samples were taken at 6, 12 and 24 hours after administration. Brain and liver tissues superoxide dismutase and glutathione peroxidase activities were measured by spectrophotometry, and blood gas parameters were measured with blood gas analyzer. As results, phenobarbital caused temporary respiratory acidosis and a decrease in brain tissue superoxide dismutase activity.
Açıklama
Anahtar Kelimeler
Phenobarbital, Superoxide Dismutase, Glutathione Peroxidase, Blood Gas Parameters, Mice
Kaynak
Revue De Medecine Veterinaire
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
152
Sayı
10
Künye
Demir, O., Yazar, E., Altunok, V., Elmas, M., Özdemir, V., (2001). Effect of Phenobarbital on Antioxidant Enzyme Activities and Blood Gas Parameters in Balb/C Mice. Revue De Medecine Veterinaire, 152(10), 723-726.
