Effect of Phenobarbital on Antioxidant Enzyme Activities and Blood Gas Parameters in Balb/C Mice

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dc.contributor.authorDemir, O.
dc.contributor.authorYazar, Enver
dc.contributor.authorAltunok, Vahdettin
dc.contributor.authorElmas, Muammer
dc.contributor.authorÖzdemir, Vural
dc.date.accessioned2020-03-26T16:37:04Z
dc.date.available2020-03-26T16:37:04Z
dc.date.issued2001
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study, effect of Phenobarbital was investigated on antioxidant enzyme activities and blood gas parameters in Balb/C mice. Forty male Balb/C mice were used. Ten mice were served as a control group, and thirty mice were administered phenobarbital (80 mg/kg body weight, orally, single administration). Blood, brain and liver samples were taken at 6, 12 and 24 hours after administration. Brain and liver tissues superoxide dismutase and glutathione peroxidase activities were measured by spectrophotometry, and blood gas parameters were measured with blood gas analyzer. As results, phenobarbital caused temporary respiratory acidosis and a decrease in brain tissue superoxide dismutase activity.en_US
dc.identifier.citationDemir, O., Yazar, E., Altunok, V., Elmas, M., Özdemir, V., (2001). Effect of Phenobarbital on Antioxidant Enzyme Activities and Blood Gas Parameters in Balb/C Mice. Revue De Medecine Veterinaire, 152(10), 723-726.
dc.identifier.endpage726en_US
dc.identifier.issn0035-1555en_US
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage723en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17529
dc.identifier.volume152en_US
dc.identifier.wosWOS:000172514700008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherECOLE NATIONALE VETERINAIRE TOULOUSEen_US
dc.relation.ispartofRevue De Medecine Veterinaireen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPhenobarbitalen_US
dc.subjectSuperoxide Dismutaseen_US
dc.subjectGlutathione Peroxidaseen_US
dc.subjectBlood Gas Parametersen_US
dc.subjectMiceen_US
dc.titleEffect of Phenobarbital on Antioxidant Enzyme Activities and Blood Gas Parameters in Balb/C Miceen_US
dc.typeArticleen_US

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