Evaluation of application of multiple needle pricks on the pathergy reaction

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dc.contributor.authorOzdemir, Mustafa
dc.contributor.authorBodur, Said
dc.contributor.authorEngin, Burhan
dc.contributor.authorBaysal, Ibrahim
dc.date.accessioned2020-03-26T17:26:50Z
dc.date.available2020-03-26T17:26:50Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground The pathergy reaction (PR) to a needle prick is a well-known feature of Behcet's disease (BD). Although PR is accepted as a major criterion in this disease, there is a lack of a standardized method to measure PR. The aim of this study was to evaluate the effect on the positive rate of PR of the application of numerous (one to six) needle pricks. Methods Six needle pricks were performed on 105 patients with BD. The results of the test were noted from the proximal to the distal region for each area of each patient. The positive rates of all combinations (one, two, three, four, five, and six needle pricks) were calculated as percentages by a computer-based program (SPSS version 13 for Windows), and the mean percentage rates were obtained. Results There was an increase in the percentage of positive PR rates in each combination relative to the former combination. When one needle prick was performed, the mean percentage positive PR rate was 13%. The positive PR rates were 19%, 24%, 28%, 30%, and 33% for two, three, four, five and six needle pricks, respectively. The greatest increase in the mean percentage of positive PR rates was detected for the application of the two needle prick combination. Conclusion There is no consensus about the number of needle pricks required to detect PR, and multiple needle pricks have been used in many studies. We suggest that two needle pricks are suitable for the PR skin test as a useful adjunct to the diagnosis of BD.en_US
dc.identifier.doi10.1111/j.1365-4632.2008.03568.xen_US
dc.identifier.endpage338en_US
dc.identifier.issn0011-9059en_US
dc.identifier.issn1365-4632en_US
dc.identifier.issue4en_US
dc.identifier.pmid18377594en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage335en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1365-4632.2008.03568.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22386
dc.identifier.volume47en_US
dc.identifier.wosWOS:000254501400004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF DERMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleEvaluation of application of multiple needle pricks on the pathergy reactionen_US
dc.typeArticleen_US

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