Evaluation of choroidal thickness using spectral-domain optical coherence tomography in patients with migraine: a comparative study

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dc.contributor.authorKaralezli, Aylin
dc.contributor.authorCelik, Guner
dc.contributor.authorKoktekir, Bengu Ekinci
dc.contributor.authorKucukerdonmez, Cem
dc.date.accessioned2020-03-26T19:05:56Z
dc.date.available2020-03-26T19:05:56Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: To assess choroidal thickness in patients with migraine and compare them with healthy controls, using spectral-domain optical coherence tomography (OCT). Methods: In this prospective case-control study, choroidal thicknesses of 20 newly diagnosed migraine patients and 20 age-and sex-matched healthy subjects were measured using a high-speed, high-resolution frequency domain (FD) OCT device (lambda = 840 nm, 26.000 A-scans/s, 5 mu m axial resolution). All patients underwent a complete ophthalmic examination before the measurements. OCT measurements were taken at the same time of day (9: 00 AM), in order to minimize the effects of diurnal variation. Results: There was a statistically significant difference in median choroidal thickness between the migraine patients (277.00 [interquartile range (IQR) 85.75] mu m) and controls (301.00 [IQR 90.50] mu m) (p = 0.012). There were significant differences at all measurement points (p<0.05 for all). Conclusions: The decreased choroidal thickness of patients with migraine might be related to the vascular pathology of the disease. Further studies are needed to evaluate the etiopathologic relationship between choroidal thickness and migraine.en_US
dc.identifier.doi10.5301/ejo.5000561en_US
dc.identifier.endpage342en_US
dc.identifier.issn1120-6721en_US
dc.identifier.issn1724-6016en_US
dc.identifier.issue4en_US
dc.identifier.pmid25633615en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage338en_US
dc.identifier.urihttps://dx.doi.org/10.5301/ejo.5000561
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32122
dc.identifier.volume25en_US
dc.identifier.wosWOS:000363047300082en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS LTDen_US
dc.relation.ispartofEUROPEAN JOURNAL OF OPHTHALMOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectChoroidal thicknessen_US
dc.subjectOptical coherence tomographyen_US
dc.subjectMigraineen_US
dc.subjectVasospasmen_US
dc.titleEvaluation of choroidal thickness using spectral-domain optical coherence tomography in patients with migraine: a comparative studyen_US
dc.typeArticleen_US

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