Effects of Zinc Supplementation on the Element Distribution in Kidney Tissue of Diabetic Rats Subjected to Acute Swimming

dc.contributor.authorSivrikaya, Abdullah
dc.contributor.authorBiçer, Mürsel
dc.contributor.authorAkil, Mustafa
dc.contributor.authorBaltacı, Abdülkerim Kasım
dc.contributor.authorMoğulkoç, Rasim
dc.date.accessioned2020-03-26T18:25:24Z
dc.date.available2020-03-26T18:25:24Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study, we report the effect of zinc supplementation on the distribution of elements in kidney tissue of diabetic rats subjected to acute swimming exercise. Diabetes was induced by two subcutaneous injections of 40 mg/kg of streptozotocin within a 24-h period. Zinc was given intraperitoneally at a dose of 6 mg/kg per day for a period of 4 weeks. The rats (n = 80) were equally divided into eight study groups: controls, zinc-supplemented, swimming, diabetic, zinc-supplemented diabetic, zinc-supplemented swimming, diabetic swimming, and zinc-supplemented diabetic swimming. The levels of lead, cobalt, molybdenum, chromium, boron, magnesium, iron, copper, calcium, zinc, and selenium were determined in the kidney tissue samples by ICP-AES. Higher molybdenum, calcium, zinc, and selenium values were found in both swimming and nonswimming diabetic rats. Significantly higher iron values were found in swimming, diabetic, diabetic swimming, and zinc-supplemented diabetic swimming rats (p < 0.001). Diabetic, zinc-supplemented diabetic, diabetic swimming, and zinc-supplemented diabetic swimming rats had the highest copper values. These results show that zinc supplementation normalized the higher levels of molybdenum, calcium, selenium, and iron levels seen in diabetic rats, indicating that zinc may have a regulatory effect on element metabolism in kidney tissue.en_US
dc.identifier.doi10.1007/s12011-011-9284-6en_US
dc.identifier.endpage199en_US
dc.identifier.issn0163-4984en_US
dc.identifier.issn1559-0720en_US
dc.identifier.issue01.03.2020en_US
dc.identifier.pmid22161314en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage195en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s12011-011-9284-6
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28001
dc.identifier.volume147en_US
dc.identifier.wosWOS:000304610400028en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHUMANA PRESS INCen_US
dc.relation.ispartofBIOLOGICAL TRACE ELEMENT RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDiabetesen_US
dc.subjectExerciseen_US
dc.subjectZinc supplementationen_US
dc.subjectKidneyen_US
dc.subjectZinc metabolismen_US
dc.titleEffects of Zinc Supplementation on the Element Distribution in Kidney Tissue of Diabetic Rats Subjected to Acute Swimmingen_US
dc.typeArticleen_US

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