Effect of luteal phase support after ovulation induction and intrauterine insemination

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dc.contributor.authorÖktem, Mesut
dc.contributor.authorAltınkaya, S. Özlem
dc.contributor.authorYımaz, Setenay Arzu
dc.contributor.authorBozkurt, Nuray
dc.contributor.authorErdem, Mehmet
dc.contributor.authorErdem, Ahmet
dc.contributor.authorGümüşlü, Seyhan
dc.date.accessioned2020-03-26T18:50:13Z
dc.date.available2020-03-26T18:50:13Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: This study aimed to evaluate the effect of luteal phase support on clinical pregnancy and live birth rates after ovulation induction and intrauterine insemination (IUI). Methods: 579 cycles from 2010 to 2013 were retrospectively evaluated. Ovarian stimulation was performed with gonadotropins, and rHCG was used for ovulation triggering. All patients received IUI. 451 cycles were supported by receiving vaginal micronized progesterone capsules (142 cycles) or vaginal progesterone gel (309 cycles) whereas 128 cycles were not supported. Results: Clinical pregnancy (20.6 versus 9.4%; p = 0.004) and live birth rates (14 versus 7%; p = 0.036) were higher for supported group than for unsupported group. Progesterone gel and micronized progesterone subgroups achieved similar clinical pregnancy and live birth rates (21.4 versus 19%, p = 0.567 and 14.2 versus 13.4%, p = 0.807; respectively). Conclusions: Luteal phase support improved the success of IUI cycles affecting both clinical pregnancy and live birth rates when gonadotropins were used for ovulation induction. The use of vaginal progesterone gel or micronized progesterone significantly improves clinical pregnancy rates. The live birth rates were higher in the progesterone gel group, but were similar in the micronized progesterone group compared to the unsupported group.en_US
dc.identifier.doi10.3109/09513590.2014.947567en_US
dc.identifier.endpage912en_US
dc.identifier.issn0951-3590en_US
dc.identifier.issn1473-0766en_US
dc.identifier.issue12en_US
dc.identifier.pmid25102275en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage909en_US
dc.identifier.urihttps://dx.doi.org/10.3109/09513590.2014.947567
dc.identifier.urihttps://hdl.handle.net/20.500.12395/30772
dc.identifier.volume30en_US
dc.identifier.wosWOS:000345213700013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofGYNECOLOGICAL ENDOCRINOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectClinical pregnancyen_US
dc.subjectintrauterine inseminationen_US
dc.subjectlive birthen_US
dc.subjectluteal supporten_US
dc.subjectprogesteroneen_US
dc.titleEffect of luteal phase support after ovulation induction and intrauterine inseminationen_US
dc.typeArticleen_US

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