Overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis with unusual initial presentation as fulminant hepatic failure

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dc.contributor.authorKayacetin, E
dc.contributor.authorKoklu, S
dc.contributor.authorTemucin, T
dc.date.accessioned2020-03-26T16:55:23Z
dc.date.available2020-03-26T16:55:23Z
dc.date.issued2004
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAutoimmune hepatitis and primary biliary cirrhosis are generally easy to discriminate on the basis of clinical, laboratory, and histological findings. The presence of anti-mitocondrial antibodies seropositivity and cholestatic clinical, laboratory, and/or histological features in patients with autoimmune hepatitis indicates the overlap syndrome of autoimmune hepatitis and primary biliary cirrhosis. Fulminant hepatic failure is an unusual initial form of presentation of autoimmune hepatitis and primary biliary cirrhosis overlap syndrome. We report the case of a 50-year-old woman with autoimmune hepatitis and primary biliary cirrhosis overlap syndrome who presented with fulminant hepatic failure. Fulminant hepatic failure has a high mortality rate and may require liver transplant. Our patient revealed a good response to corticosteroid and ursodeoxycholic acid therapy. It is important to identify and distinguish autoimmune hepatitis and variant syndromes from other forms of liver disease because of response to corticosteroid therapy. (C) 2004 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.dld.2003.09.023en_US
dc.identifier.endpage422en_US
dc.identifier.issn1590-8658en_US
dc.identifier.issue6en_US
dc.identifier.pmid15248383en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage419en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.dld.2003.09.023
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19153
dc.identifier.volume36en_US
dc.identifier.wosWOS:000222016400010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPACINI EDITOREen_US
dc.relation.ispartofDIGESTIVE AND LIVER DISEASEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectautoimmune hepatitisen_US
dc.subjectfulminant hepatic failureen_US
dc.subjectprimary biliary cirrhosisen_US
dc.titleOverlap syndrome of primary biliary cirrhosis and autoimmune hepatitis with unusual initial presentation as fulminant hepatic failureen_US
dc.typeArticleen_US

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