Melatonin supplementation to rats subjected to acute swimming exercise: Its effect on plasma lactate levels and relation with zinc

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dc.contributor.authorKaya, O
dc.contributor.authorGokdemir, K
dc.contributor.authorKilic, M
dc.contributor.authorBaltaci, AK
dc.date.accessioned2020-03-26T17:03:53Z
dc.date.available2020-03-26T17:03:53Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractOBJECTIVE: The objective of the present study is to examine the effect on melatonin supplementation on plasma lactate levels and its relation with zinc in rats subjected to acute swimming exercise. METHODS:Thirty adult male rats of Spraque-Dawley species were allocated to 3 groups, each containing an equal number of rats: general control group which was not subjected to any procedure (Group 1), the group which was subjected to 30 minutes acute swimming exercise (Group 2), and the group which was subjected to 30 minutes acute swimming exercise after 4-week intraperitoneal (i.p.) melatonin (3 mg/kg/day) supplementation. Lactate and zinc levels in the plasma were studied in the blood samples taken from the experimental animals by decapitation method. RESULTS:The animals in the control group, which was not subjected to any procedure (group 1), had higher lactate levels than those in groups 2 and 3 (p < 0,05). Lactate levels in the swimming group supplemented with melatonin (group 3) were lower than those in group 2 (swimming group) (p < 0,05). The highest plasma zinc levels were obtained in the melatonin-supplemented swimming group (group 3) (p < 0,05). Group 2 (swimming control) had the lowest plasma zinc levels (p < 0,05). CONCLUSION:Results of the study demonstrate that melatonin supplementation to rats subjected to acute swimming exercise reduces lactate levels, thereby delaying exhaustion. Increased zinc levels may be mediating this melatonin effect.en_US
dc.identifier.endpage266en_US
dc.identifier.issn0172-780Xen_US
dc.identifier.issue01.02.2020en_US
dc.identifier.pmid16648794en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage263en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20579
dc.identifier.volume27en_US
dc.identifier.wosWOS:000238667700046en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMAGHIRA & MAAS PUBLICATIONSen_US
dc.relation.ispartofNEUROENDOCRINOLOGY LETTERSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectmelatoninen_US
dc.subjectacute swimming exerciseen_US
dc.subjectlactateen_US
dc.subjectzincen_US
dc.titleMelatonin supplementation to rats subjected to acute swimming exercise: Its effect on plasma lactate levels and relation with zincen_US
dc.typeArticleen_US

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