Functional components, antidiabetic, anti-Alzheimer's disease, and antioxidant activities of Salvia syriaca L.

Küçük Resim Yok

Tarih

2017

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

TAYLOR & FRANCIS INC

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Antidiabetic, anti-Alzheimer, general toxicity, and antioxidant activities of Salvia syriaca were evaluated. Phytochemical composition of the essential oil and methanolic extract of the plant were identified using gas chromatography-mass spectrometry and reverse-phase high-performance liquid chromatography-diode array detector techniques, respectively. Essential oil of S. syriaca exhibited strong cytotoxicity, antioxidant, a-amylase, and a-glucosidase inhibitory activities. Gas chromatography-mass spectrometry analysis showed that spathulenol (87.4%), isospathulenol (7.6%), and bornyl acetate (2.7%) are the major compounds in essential oil. High-performance liquid chromatography analysis indicated that rutin, quercetin, apigenin, rosmarinic acid, and ferulic acid are the most abundant phenolic components. S. syriaca could be considered as a valuable source of bioactive natural compounds for functional foods, medical, and pharmaceutical applications.

Açıklama

Anahtar Kelimeler

Salvia syriaca, Alzheimer's, disease, Diabetes mellitus, Phenolic compounds, Rutin, Spathulenol

Kaynak

INTERNATIONAL JOURNAL OF FOOD PROPERTIES

WoS Q Değeri

Q2

Scopus Q Değeri

Q2

Cilt

20

Sayı

8

Künye