Functional components, antidiabetic, anti-Alzheimer's disease, and antioxidant activities of Salvia syriaca L.

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dc.contributor.authorBahadori, Mir Babak
dc.contributor.authorDinparast, Leila
dc.contributor.authorZengin, Gökhan
dc.contributor.authorSarikurkcu, Cengiz
dc.contributor.authorBahadori, Shahram
dc.contributor.authorAsghari, Behvar
dc.contributor.authorMovahhedin, Nasrin
dc.date.accessioned2020-03-26T19:41:47Z
dc.date.available2020-03-26T19:41:47Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAntidiabetic, anti-Alzheimer, general toxicity, and antioxidant activities of Salvia syriaca were evaluated. Phytochemical composition of the essential oil and methanolic extract of the plant were identified using gas chromatography-mass spectrometry and reverse-phase high-performance liquid chromatography-diode array detector techniques, respectively. Essential oil of S. syriaca exhibited strong cytotoxicity, antioxidant, a-amylase, and a-glucosidase inhibitory activities. Gas chromatography-mass spectrometry analysis showed that spathulenol (87.4%), isospathulenol (7.6%), and bornyl acetate (2.7%) are the major compounds in essential oil. High-performance liquid chromatography analysis indicated that rutin, quercetin, apigenin, rosmarinic acid, and ferulic acid are the most abundant phenolic components. S. syriaca could be considered as a valuable source of bioactive natural compounds for functional foods, medical, and pharmaceutical applications.en_US
dc.description.sponsorshipUrmia University of Medical sciences [1394-01-36-2104]en_US
dc.description.sponsorshipFinancial support by the Urmia University of Medical sciences is gratefully acknowledged (Project number: 1394-01-36-2104).en_US
dc.identifier.doi10.1080/10942912.2016.1218893en_US
dc.identifier.endpage1772en_US
dc.identifier.issn1094-2912en_US
dc.identifier.issn1532-2386en_US
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1761en_US
dc.identifier.urihttps://dx.doi.org/10.1080/10942912.2016.1218893
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35143
dc.identifier.volume20en_US
dc.identifier.wosWOS:000402969700007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS INCen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF FOOD PROPERTIESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectSalvia syriacaen_US
dc.subjectAlzheimer'sen_US
dc.subjectdiseaseen_US
dc.subjectDiabetes mellitusen_US
dc.subjectPhenolic compoundsen_US
dc.subjectRutinen_US
dc.subjectSpathulenolen_US
dc.titleFunctional components, antidiabetic, anti-Alzheimer's disease, and antioxidant activities of Salvia syriaca L.en_US
dc.typeArticleen_US

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