Release of NT-pro brain natriuretic peptide in children before and after adenotonsillectomy

Basit Öğe Kaydı
dc.contributor.authorOran, Bulent
dc.contributor.authorOzturk, Kayhan
dc.contributor.authorCimen, Derya
dc.contributor.authorVatansev, Husamettin
dc.contributor.authorBulut, Serap
dc.contributor.authorArslan, Derya
dc.date.accessioned2020-03-26T18:43:10Z
dc.date.available2020-03-26T18:43:10Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: To measure serum B-type natriuretic peptide, especially N-terminal segment of its prohormone (NT-proBNP) and pulmonary arterial pressure levels and to determine whether NT-proBNP concentrations correlate with pulmonary arterial pressure levels in children before and after adenotonsillectomy. Methods: Twenty children with adenoid and tonsil hypertrophy and 20 healthy subjects were included in the study. Transthoracic echocardiography was performed in all patients to assess pulmonary artery systolic and diastolic pressure with cardiac dysfunction. The NT-proBNP was analyzed for correlation with pulmonary artery pressure. Results: Our results showed that prohormone serum concentrations and pulmonary arterial pressures were significantly higher in the study group than in the control group at the preoperative evaluation. A significant decrease was detected among patients after surgery (p < 0.05). There was no significant difference between the study and control groups for prohormone serum concentration and pulmonary arterial pressure at the postoperative evaluation (p > 0.05). Conclusion: We found increased serum prohormone levels and height pulmonary artery pressures in the children with adenoid and tonsil hypertrophy when comparing with healthy subjects. Our study supported that increased serum prohormone levels and pulmonary artery pressures as a result of adenoid and tonsil hypertrophy are reversible. Pediatric cardiologs and otolaryngologs should keep in mind an increased pulmonary artery pressure during management of children with adenoid and tonsil hypertrophy. Furthermore, Doppler echocardiography may be useful in the monitoring of pulmonary arterial pressure and in the follow-up of surgical outcome of children with adenoid and tonsil hypertrophy. (C) 2013 Elsevier Ireland Ltd. All rights reserved.en_US
dc.description.sponsorshipSelcuk University Scientific Research Found (BAP project )Selcuk University [2011/10401121]en_US
dc.description.sponsorshipThis study has been supported by a research grant of Selcuk University Scientific Research Found (BAP project no. 2011/10401121).en_US
dc.identifier.doi10.1016/j.ijporl.2013.01.007en_US
dc.identifier.endpage669en_US
dc.identifier.issn0165-5876en_US
dc.identifier.issn1872-8464en_US
dc.identifier.issue5en_US
dc.identifier.pmid23415956en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage666en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.ijporl.2013.01.007
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29780
dc.identifier.volume77en_US
dc.identifier.wosWOS:000318384000008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER IRELAND LTDen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectN-terminal pro B-type natriuretic peptideen_US
dc.subjectAdenoid hypertrophyen_US
dc.subjectChildhooden_US
dc.subjectPulmonary artery pressureen_US
dc.titleRelease of NT-pro brain natriuretic peptide in children before and after adenotonsillectomyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu