Outcomes of Gamma Knife Treatment for Solid Intracranial Hemangioblastomas

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dc.contributor.authorKarabağlı, Hakan
dc.contributor.authorGenç, Ali
dc.contributor.authorKarabağlı, Pınar
dc.contributor.authorAbacıoğlu, Ufuk
dc.contributor.authorŞeker, Aşkın
dc.contributor.authorKılıç, Türker
dc.date.accessioned2020-03-26T18:04:47Z
dc.date.available2020-03-26T18:04:47Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to examine the results of gamma knife radiosurgery for 13 patients with residual/recurrent or newly diagnosed solid hemangioblastomas. The 13 patients had 34 solid hemangioblastomas, and all patients underwent gamma knife radiosurgery. Seven patients had von Hippel-Lindau disease and six had sporadic disease. When individual lesions were considered, the overall mean dose at the tumor periphery was 15.8 Gy (range: 12-25 Gy) and the average maximum tumor dose was 31.6 Gy (range: 24-50 Gy). The mean duration of follow-up with MRI was 50.2 months. At the last follow-up evaluation, growth control was achieved for all tumors (partial remission in three tumors [8.8%] and no change in 31 tumors [91.2%]). No radiation-related complications were encountered. Our findings reinforce the view that gamma knife radiosurgery is effective and safe for the management of solid hemangioblastomas with a diameter less than 3 cm, whether they are sporadic or associated with von Hippel-Lindau disease. The high response rate and lack of any radiation-induced side-effects confirms the suitability of the doses used in the present study.en_US
dc.description.sponsorshipTurkish Society for Brain Research; Turkish Academy of SciencesTurkish Academy of Sciencesen_US
dc.description.sponsorshipThis study was supported by the Turkish Society for Brain Research and the Turkish Academy of Sciences.en_US
dc.identifier.citationKarabağlı, H., Genç, A., Karabağlı, P., Abacıoğlu, U., Şeker, A., Kılıç, T., (2010). Outcomes of Gamma Knife Treatment for Solid Intracranial Hemangioblastomas. Journal of Clinical Neuroscience, (17), 706-710. Doi: 10.1016/j.jocn.2009.09.028
dc.identifier.doi10.1016/j.jocn.2009.09.028en_US
dc.identifier.endpage710en_US
dc.identifier.issn0967-5868en_US
dc.identifier.issn1532-2653en_US
dc.identifier.pmid20303274en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage706en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jocn.2009.09.028
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25139
dc.identifier.volume17en_US
dc.identifier.wosWOS:000278084900005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKarabağlı, Hakan
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofJournal of Clinical Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectGamma knifeen_US
dc.subjectHemangioblastomaen_US
dc.subjectRadiosurgeryen_US
dc.subjectVon Hippel-Lindau diseaseen_US
dc.titleOutcomes of Gamma Knife Treatment for Solid Intracranial Hemangioblastomasen_US
dc.typeArticleen_US

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