Late-Onset Adenosine Deaminase Deficiency Presenting with Heck's Disease
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Dosyalar
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SPRINGER
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Focal epithelial hyperplasia, also known as Heck's disease, is a rare but distinctive entity of viral etiology with characteristic clinical and histopathological features. It is a benign, asymptomatic disease of the oral mucosa caused by human papilloma viruses (HPV). Previous studies postulated an association between these lesions and immunodeficiency. Genetic deficiency of adenosine deaminase (ADA) results in varying degrees of immunodeficiency, including neonatal onset severe combined immunodeficiency (ADA-SCID), and milder, later onset immunodeficiency. We report a 12-year-old girl with the late onset-ADA deficiency presenting with Heck's disease. Our case report should draw attention to the possibility of immunodeficiency in patients with HPV-induced focal epithelial hyperplasia.
Açıklama
Anahtar Kelimeler
Late-onset adenosine deaminase deficiency, Focal epithelial hyperplasia, Human papilloma virus
Kaynak
European Journal of Pediatrics
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
169
Sayı
8
Künye
Artaç, H., Göktürk, B., Bozdemir, Ş. E., Toy, H., Van Der Burg, M., Santisteban, I., Hershfield, M., Reisli, İ., (2010). Late-Onset Adenosine Deaminase Deficiency Presenting with Heck's Disease. European Journal of Pediatrics, 169(8), 1033-1036. DOI: 10.1007/s00431-009-1131-9
