Topical and Long-Acting Local Anesthetic for Prostate Biopsy: A Prospective Randomized Placebo-Controlled Study

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dc.contributor.authorYurdakul, Talat
dc.contributor.authorTaspinar, Bulent
dc.contributor.authorKilic, Ozcan
dc.contributor.authorKilinc, Mehmet
dc.contributor.authorSerarslan, Alparslan
dc.date.accessioned2020-03-26T17:40:58Z
dc.date.available2020-03-26T17:40:58Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To determine the efficacy of intrarectal lidocaine gel alone and a combination of lidocaine gel with 2 different longer-acting local anesthetic (LA) agents that were injected into the periprostatic area before transrectal ultrasound-guided prostate biopsy. Patients and Methods: One hundred patients undergoing transrectal prostate biopsy were randomized into 4 groups of 25 patients each. Before the biopsy, group 1 received no local anesthesia, group 2 received 2% lidocaine gel intrarectally, group 3 received intrarectal lidocaine gel and 5 ml bupivacaine (0.25%) injected into periprostatic area, and group 4 received lidocaine gel intrarectally and a 5-ml ropivacaine injection (0.25%) in the same location as group 3. Pain levels during and after the biopsy were assessed by using a 10-point linear visual analog scale (VAS). Results: Patients in groups 3 and 4 had significantly lower VAS scores than those in groups 1 and 2, both during and 1 h after biopsy. There were no differences in the pain scores between groups 1 and 2. Conclusion: The combination of intrarectal lidocaine gel and periprostatic longer-acting LA agents significantly reduces the pain related to prostate biopsy, whereas intrarectal lidocaine gel administration alone does not reduce pain. Thus, administration of the periprostatic longer-acting LA agents alone is adequate. Copyright (C) 2009 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000230015en_US
dc.identifier.endpage154en_US
dc.identifier.issn0042-1138en_US
dc.identifier.issn1423-0399en_US
dc.identifier.issue2en_US
dc.identifier.pmid19752608en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage151en_US
dc.identifier.urihttps://dx.doi.org/10.1159/000230015
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23988
dc.identifier.volume83en_US
dc.identifier.wosWOS:000269788900005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKARGERen_US
dc.relation.ispartofUROLOGIA INTERNATIONALISen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectProstateen_US
dc.subjectBiopsyen_US
dc.subjectPainen_US
dc.subjectLocal anesthesiaen_US
dc.titleTopical and Long-Acting Local Anesthetic for Prostate Biopsy: A Prospective Randomized Placebo-Controlled Studyen_US
dc.typeArticleen_US

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